Abualhasan Murad, Awad Mai, Sweileh Waleed
Faculty of Pharmacy, An-Najah National University, P.O. Box 7, Nablus, State of Palestine.
Department of Physiology and Pharmacology/Toxicology, Division of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, State of Palestine.
BMC Health Serv Res. 2025 Jul 2;25(1):891. doi: 10.1186/s12913-025-13028-6.
Diabetes mellitus is a common metabolic disorder marked by hyperglycemia. Studying the use of anti-diabetic medications is essential for promoting proper drug use and improving healthcare planning.
This study aims to examine the drug utilization patterns and prescribing practices among Type 2 Diabetic Patients in Palestine. Specifically, it seeks to identify the most commonly prescribed medications, evaluate adherence to clinical guidelines, and assess factors influencing drug utilization at diabetes healthcare centers operated by the Ministry of Health (MOH) in Palestine.
A cross-sectional survey was conducted among 400 randomly selected patients with T2DM attending diabetic clinics in the northern and central regions of the West Bank, Palestine. Data on prescribing patterns and medication adherence were collected through patient interviews, and ethical guidelines were strictly followed throughout the study.
The study found that metformin was the most frequently prescribed initial therapy for patients with T2DM. Medication adherence was notably high, with 68% of patients consistently taking their medications as directed, although 24% reported occasionally forgetting to do so. Approximately 90% of patients followed the prescribed dosage exactly as instructed. There were no statistically significant differences in metformin prescribing patterns across the regions; prescriptions for glimepiride varied significantly (p = 0.01). Combination therapies were also commonly used.
This research can enhance our understanding of diabetes treatment methods, patient adherence, and the factors influencing prescription decisions. Ultimately, this will support the development of more effective strategies for diabetes management.
糖尿病是一种以高血糖为特征的常见代谢紊乱疾病。研究抗糖尿病药物的使用对于促进合理用药和改善医疗规划至关重要。
本研究旨在调查巴勒斯坦2型糖尿病患者的药物使用模式和处方习惯。具体而言，它旨在确定最常处方的药物，评估对临床指南的依从性，并评估在巴勒斯坦卫生部（MOH）运营的糖尿病医疗中心影响药物使用的因素。
对巴勒斯坦约旦河西岸北部和中部地区糖尿病诊所随机抽取的400例2型糖尿病患者进行了横断面调查。通过患者访谈收集了处方模式和药物依从性的数据，并且在整个研究过程中严格遵循伦理准则。
研究发现二甲双胍是2型糖尿病患者最常处方的初始治疗药物。药物依从性显著较高，68%的患者按指示持续服药，尽管24%的患者报告偶尔会忘记服药。约90%的患者完全按照指示服用规定剂量。各地区二甲双胍的处方模式没有统计学上的显著差异；格列美脲的处方差异显著（p = 0.01）。联合治疗也常用。
本研究可以增强我们对糖尿病治疗方法、患者依从性以及影响处方决策因素的理解。最终，这将支持制定更有效的糖尿病管理策略。
