Zhang Jiao, Li Lihua, Xi Huinan, Wang Qi, Jiang Fan, Sun Xin, Qiao Xuebin, Xu Aijun
School of Health Economics and Management, Nanjing University of Chinese Medicine, Nanjing, China.
Jiangsu Research Center for Major Health Risk Management and TCM Control Policy, Nanjing University of Chinese Medicine, Nanjing, China.
BMC Complement Med Ther. 2025 Jul 2;25(1):218. doi: 10.1186/s12906-025-04937-4.
Patient preferences have gradually been incorporated into decisions about cancer treatment regimens over recent years. Meanwhile, the efficacy of traditional Chinese medicine (TCM) in cancer-related treatments has been recognized. This study aimed to estimate the specific preferences of cancer patients for TCM treatment regimens to inform the clinical decision-making process for health promotion.
This cross-sectional investigation employed a discrete choice experiment (DCE) methodology to assess TCM treatment regimens preferences among cancer patients. The DCE systematically elicits participants' preferences through the sequential presentation of hypothetical clinical scenarios with varying combinations of therapeutic attributes, with subsequent data analysis conducted using mixed logit models. We applied this methodology to examine cancer patient preferences regarding different TCM treatment regimens. Additionally, a subgroup analysis of sex groups was conducted to identify potential preference variations across demographic groups.
In total, 728 participants completed the questionnaire and passed the consistency test. Control rate of disease, gastrointestinal adverse effects, mode of administration, treatment duration, quality of life, and monthly out-of-pocket cost had a significant impact on the TCM treatment preference of the participating cancer patients. Preferences almost remained consistent irrespective of the participants' sex.
Differences in treatment have an impact on the preferences of TCM treatment in cancer patients. Cancer patients' preferences related to the control rate of disease and quality of life should be prioritized and considered in TCM treatment decision-making.
近年来,患者偏好已逐渐被纳入癌症治疗方案的决策中。与此同时,中医在癌症相关治疗中的疗效已得到认可。本研究旨在评估癌症患者对中医治疗方案的具体偏好,以为促进健康的临床决策过程提供参考。
本横断面调查采用离散选择实验(DCE)方法来评估癌症患者对中医治疗方案的偏好。DCE通过依次呈现具有不同治疗属性组合的假设临床场景,系统地引出参与者的偏好,随后使用混合逻辑模型进行数据分析。我们应用此方法来研究癌症患者对不同中医治疗方案的偏好。此外,对性别组进行了亚组分析,以确定不同人口统计学组之间潜在的偏好差异。
共有728名参与者完成了问卷并通过了一致性检验。疾病控制率、胃肠道不良反应、给药方式、治疗持续时间、生活质量和每月自付费用对参与研究的癌症患者的中医治疗偏好有显著影响。无论参与者的性别如何,偏好几乎保持一致。
治疗差异会影响癌症患者对中医治疗的偏好。在中医治疗决策中,应优先考虑癌症患者对疾病控制率和生活质量的偏好。