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在处理B型主动脉夹层时早期血管内介入治疗和基于指南的心脏康复的重要性。

The Importance of Early Endovascular Intervention and Guideline-Based Cardiac Rehabilitation When Managing Type-B Aortic Dissection.

作者信息

Chadda Daniel, Khanipour Ramtin, Rehman Mohammad Z, Boadu Charles, Chadda Nader

机构信息

Cardiology, George Washington University, Washington, D.C., USA.

Internal Medicine and Cardiology, HCA Florida Bayonet Point Hospital, University of South Florida, Hudson, USA.

出版信息

Cureus. 2025 Jun 1;17(6):e85206. doi: 10.7759/cureus.85206. eCollection 2025 Jun.

Abstract

Most type-B aortic dissections are managed medically, except in certain situations such as descending aortic rupture, malperfusion, hypertension refractory to medical therapy (β-blockers and dihydropyridine calcium channel blockers), aneurysmal dilation, expansion, rupture, or impending rupture, where surgical intervention or an endovascular procedure is recommended as the primary method of treatment. However, there are scenarios where a type-B aortic dissection meets the criteria for surgical or endovascular intervention, but the patient is a poor surgical candidate due to the presence of numerous comorbidities (e.g., advanced age, hemodynamic instability, or the absence of a sufficient "landing zone" for intervention). In the following case report, we describe a 76-year-old female who presents with type-B aortic dissection extending to the distal left iliac artery. During her hospitalization, the patient was managed medically. Unfortunately, on day five of hospitalization, the patient developed sudden-onset chest pain followed by cardiac arrest shortly after her cardiac rehabilitation session. Considering how extensive her type-B aortic dissection was, it is hypothesized that due to physical exertion, there was an acute-onset retrograde expansion of the flap leading to sudden cardiac death. This emphasizes the importance of early surgical intervention as well as having a strict guideline regarding the level of physical exertion that such patients can undergo.

摘要

大多数B型主动脉夹层采用内科治疗,除非在某些情况下,如降主动脉破裂、灌注不良、药物治疗(β受体阻滞剂和二氢吡啶类钙通道阻滞剂)难以控制的高血压、动脉瘤样扩张、扩展、破裂或即将破裂,此时建议手术干预或血管内介入治疗作为主要治疗方法。然而,在某些情况下,B型主动脉夹层符合手术或血管内介入治疗的标准,但由于存在多种合并症(如高龄、血流动力学不稳定或缺乏足够的介入“着陆区”),患者并非手术的合适人选。在以下病例报告中,我们描述了一名76岁女性,其B型主动脉夹层延伸至左髂总动脉远端。在住院期间,该患者接受了内科治疗。不幸的是,住院第5天,患者在心脏康复训练后不久突然出现胸痛,随后心脏骤停。考虑到她的B型主动脉夹层范围广泛,据推测,由于体力活动,瓣片急性逆行扩展导致心源性猝死。这强调了早期手术干预的重要性,以及针对此类患者体力活动水平制定严格指导原则的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37bd/12213474/5a3b692af979/cureus-0017-00000085206-i01.jpg

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