Lovasik J V, Spafford M, Szymkiw M
Vision Res. 1985;25(4):599-608. doi: 10.1016/0042-6989(85)90166-x.
The amplitudes and implicit times of the P-1 component of monocular transient pattern VERs elicited by reversing checkerboard targets were measured in 6 conditions: (1) Ocular accommodation (Ao) elicited by minus power ophthalmic lenses; (2) Ao stimulated by minus lenses with the natural pupil of the test eye dilated and replaced by an artificial pupil; (3) accommodative demand and pupil size fixed with retinal image size (Ir) changed by afocal minifying lenses, (4) accommodative demand and Ir fixed but pupil size changed; (5) Ao elicited by minus lenses for three sizes of reversing checkerboards, and (6) Ao elicited by minus lenses for a constant checkerboard size with three check sizes. The observed decrease in VER amplitude with Ao could not be attributed entirely to the effects of pupil size or Ir. The rate at which the amplitude of P-1 decreased with Ao was not affected by checkerboard check size, but was closely correlated with checkerboard field size. The implicit time of P-1 first decreased slightly below baseline values at low and moderate levels of Ao and then tended to increase significantly at higher levels. The increase in implicit time at high levels of Ao could be explained adequately by the effects of pupil size alone on the VER. However, where Ao occurred without pupillary miosis, the increase in implicit time could only be explained by focusing error.
在6种情况下测量了由反转棋盘格目标诱发的单眼瞬态图形视觉诱发电位（VER）P-1成分的波幅和潜伏时间：（1）用负屈光度眼镜片诱发的眼调节（Ao）；（2）在测试眼的自然瞳孔扩张并用人工瞳孔替代的情况下，用负镜片刺激Ao；（3）通过无焦缩小镜片改变视网膜像大小（Ir），同时固定调节需求和瞳孔大小；（4）固定调节需求和Ir，但改变瞳孔大小；（5）用负镜片对三种大小的反转棋盘格诱发Ao；（6）用负镜片对具有三种方格大小的恒定棋盘格大小诱发Ao。观察到的VER波幅随Ao的降低不能完全归因于瞳孔大小或Ir的影响。P-1波幅随Ao降低的速率不受棋盘格方格大小的影响，但与棋盘格视野大小密切相关。P-1的潜伏时间在低和中等水平的Ao时首先略低于基线值下降，然后在较高水平时趋于显著增加。在高水平的Ao时潜伏时间的增加仅由瞳孔大小对VER的影响就可以充分解释。然而，在没有瞳孔缩小的情况下发生Ao时，潜伏时间的增加只能用聚焦误差来解释。
