Simonov M Ia, Gal'perin Iu M, Azarov Ia B
Vopr Pitan. 1985 Jul-Aug(4):30-4.
The concentration of chyme ingredients and volumetric velocity of the chyme transfer from the duodenum to the jejunum were investigated in experiments on normal preoperated dogs with fistulas implanted into the stomach, duodenum and jejunum after feeding different diets throughout the entire process of active digestion. It has been established that as a result of exchange between the medium filling the gastroduodenal part of the alimentary tract and blood, an enteral medium is formed in the duodenum, with the composition of this medium being relatively constant as regards the concentration and constituent ingredients. It has been also shown that the direction of the balanced flows of the nutrients depends on their concentration in the diet and that both immediate exchange of substances between the enteral and internal media, which is effected according to the concentration gradient, and regulatory alterations in the secretion are involved in homeostasis of the enteral medium.
在对正常的术前已植入瘘管至胃、十二指肠和空肠的犬进行的实验中,在整个主动消化过程中投喂不同饮食后,研究了食糜成分的浓度以及食糜从十二指肠转移至空肠的体积速度。已经确定,由于填充消化道胃十二指肠部分的介质与血液之间的交换,在十二指肠中形成了肠内介质,就浓度和组成成分而言,该介质的组成相对恒定。还表明,营养物质平衡流动的方向取决于它们在饮食中的浓度,并且根据浓度梯度进行的肠内介质与体内介质之间的直接物质交换以及分泌的调节性改变都参与了肠内介质的稳态。