Knyrim K, Hagenmüller F, Classen M
Z Gastroenterol. 1985 Feb;23(2):74-8.
We report the history and endoscopic treatment of a 63 year old female patient with chronic pancreatitis and stenosis of the pancreatic duct. Several operations of the biliary system had been performed in this patient previously (cholecystectomy 1964, choledochoduodenostomy 1972, revision of the choledochoduodenostomy 1974). In 1976 a chronic pancreatitis and a prepapillary stenosis of the Ductus wirsungianus has been diagnosed by clinical and endoscopic radiological findings. In order to relief pain we performed endoscopic sphincterotomies of the pancreatic duct orifice in 1976, 1977 and 1979. Because of relapsing abdominal pain and worsening of the pancreatic duct stenosis we performed two endoscopic balloon dilations of the proximal pancreatic duct at 20 months intervals. These lowered the pancreatoduodenal pressure difference from 40 mm Hg to normal values (below 13 mm Hg) over more than 12 months. Until today only few--less than ten--endoscopic dilations of the pancreatic duct orifice have been reported. A final estimation of this procedure is premature. However our case should stimulate other groups to consider this new form of therapy in selected patients with chronic pancreatitis and marked stenosis of the pancreatic duct.
我们报告了一名63岁慢性胰腺炎合并胰管狭窄女性患者的病史及内镜治疗情况。该患者此前已接受过多次胆道系统手术(1964年行胆囊切除术,1972年行胆总管十二指肠吻合术,1974年对胆总管十二指肠吻合术进行修复)。1976年,根据临床及内镜放射学检查结果诊断为慢性胰腺炎及胰腺导管乳头前狭窄。为缓解疼痛,我们于1976年、1977年和1979年对胰管开口进行了内镜括约肌切开术。由于腹痛复发且胰管狭窄加重,我们每隔20个月对胰管近端进行了两次内镜球囊扩张。在超过12个月的时间里,这些操作使胰十二指肠压力差从40毫米汞柱降至正常水平(低于13毫米汞柱)。迄今为止,仅有少数(不到十例)胰管开口内镜扩张的报道。对该手术的最终评估尚不成熟。然而,我们的病例应能促使其他团队在选定的慢性胰腺炎合并明显胰管狭窄患者中考虑这种新的治疗方式。