Kheradpir M H, Alebouyeh M
Z Kinderchir. 1985 Aug;40(4):195-8. doi: 10.1055/s-2008-1059772.
From 1981-1982 we performed partial splenectomy in 6 children with beta-thalassaemia major as an alternative to splenectomy to reduce transfusion and to preserve some splenic immune function. In two of our young patients with transfusion requirements of 150 ml/kg/year, where more than 2/3 of the spleen was removed, the number of transfusions was significantly reduced with prolonged intervals, haemoglobin rose with a marked improvement in the general condition, nutrition and growth. There were no major post-operative complications. 2 years' follow-up revealed no infection without sepsis prophylaxis.
1981年至1982年期间，我们对6名重型β地中海贫血患儿实施了部分脾切除术，以此作为脾切除术的替代方法，以减少输血并保留部分脾脏免疫功能。在我们的两名年轻患者中，其每年的输血量为150毫升/千克，超过三分之二的脾脏被切除，输血次数显著减少，间隔时间延长，血红蛋白升高，总体状况、营养和生长情况有明显改善。术后未出现重大并发症。两年的随访显示，在未进行败血症预防的情况下未发生感染。
