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[大鼠颈动脉体的化学感受器功能与代谢]

[Chemoreceptor function and metabolism of the carotid body in the rat].

作者信息

Samoĭlov V O, Ponomarenko G N

出版信息

Zh Evol Biokhim Fiziol. 1985 Sep-Oct;21(5):516-21.

PMID:4060945
Abstract

Using fluorimetric and polarographic determination of cell respiration, metabolic reactions of the carotid body of rats to adequate stimulation have been revealed. Functional relationships of the dose--effect type, which were found for these reactions, may be approximated by equations which are similar to those describing the unconditioned reflexes from the carotid chemoreceptors. However, reactions of the metabolics systems of the carotid body account for the perception of not all chemical stimuli, but only of acids and some alkaloids. These data reveal the heteregeneity of the carotid chemosensory system not only in the amphibians (which was known earlier), but in mammals as well.

摘要

通过荧光法和极谱法测定细胞呼吸,已揭示了大鼠颈动脉体对适当刺激的代谢反应。这些反应所呈现的剂量 - 效应类型的功能关系,可用类似于描述来自颈动脉化学感受器的非条件反射的方程式来近似。然而,颈动脉体代谢系统的反应并非对所有化学刺激都有感知,而仅对酸和某些生物碱有感知。这些数据表明,颈动脉化学感受系统不仅在两栖动物中(这一点先前已为人所知)具有异质性,在哺乳动物中也是如此。

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