[一项实验中通过检测粪便中的β-天冬氨酰甘氨酸对菌群失调进行快速诊断]
[Rapid diagnosis of dysbacteriosis by detecting beta-aspartylglycine in the feces in an experiment].
作者信息
Chakhava O V, Ruban S Z, Shustrova N M, Iur'eva E A
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1985 Aug(8):15-8.
In experiments on Fischer rats (F-344), both with common microflora and germ-free, the influence of the systemic destination of different antibiotics (tetracycline + ampicillin, gentamicin + kefzol, gentamicin, fradizine) on the intestinal microflora, the content of beta-ospartylglycine in feces and the colonization resistance of the intestinal tract to Staphylococcus aureus B-243 and Pseudomonas aeruginosa No. 93 has been studied. The early appearance of beta-aspartyl-glycine in the supernatant of fecal samples has been shown to be the first sign of dysbacteriosis and to indicate the decrease of the colonization resistance of the intestine to opportunistic bacteria.
在对普通菌群和无菌的Fischer大鼠（F-344）进行的实验中，研究了不同抗生素（四环素+氨苄青霉素、庆大霉素+头孢唑林、庆大霉素、弗氏菌素）的全身作用对肠道微生物群、粪便中β-天冬氨酰甘氨酸含量以及肠道对金黄色葡萄球菌B-243和铜绿假单胞菌93号的定植抵抗力的影响。粪便样本上清液中β-天冬氨酰甘氨酸的早期出现已被证明是菌群失调的第一个迹象，并表明肠道对机会性细菌的定植抵抗力下降。
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