Linderholm H, Osterman G, Teien D
Acta Med Scand. 1985;218(2):181-8. doi: 10.1111/j.0954-6820.1985.tb08845.x.
In a preoperative evaluation, 35 consecutive patients with aortic stenosis were examined by means of exercise ECG, Doppler and direct manometric measurements of the pressure difference over the aortic valve (delta P) and angiocardiography. Coronary artery disease (CAD) was found in 43% of the patients. Those with CAD had a lower mean maximum physical performance expressed as a percentage of the normal value (Wmax%), larger ST depressions and a higher effort angina (EA) score at the exercise test than the non-CAD group. Mean delta P was equal in the two groups. A myocardial coronary obstruction score covariated positively with a coronary insufficiency index (CT index = 100 X STdepr/Wmax%) and the EA score. There was no correlation between delta P and the EA score or the CI index. A CI index less than 3 and an EA score less than 2 were found in 49% of the patients and excluded the presence of CAD with a predictive accuracy of 88%, a better diagnostic complement to coronary arteriography than a history of EA.
在一项术前评估中,对35例连续性主动脉瓣狭窄患者进行了运动心电图、多普勒检查、直接测量主动脉瓣上压差(ΔP)以及心血管造影。43%的患者发现患有冠状动脉疾病(CAD)。与无CAD组相比,患有CAD的患者在运动试验中以正常价值百分比表示的平均最大体能表现(Wmax%)更低,ST段压低更大,劳力性心绞痛(EA)评分更高。两组的平均ΔP相等。心肌冠状动脉阻塞评分与冠状动脉供血不足指数(CT指数=100×STdepr/Wmax%)和EA评分呈正相关。ΔP与EA评分或CI指数之间无相关性。49%的患者CI指数小于3且EA评分小于2,这排除了CAD的存在,预测准确率为88%,是比EA病史更好的冠状动脉造影诊断补充。