Bahadori Arya, Woods Jessie, Yuan Lance, Emmett Louise, Yaxley John, Roberts Matthew J
Department of Urology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Department of Theranostics and Nuclear Medicine, St Vincent's Hospital, Sydney, Australia.
Prostate Int. 2025 Jun;13(2):67-73. doi: 10.1016/j.prnil.2025.03.003. Epub 2025 Mar 18.
Prostate biopsy prior to radical treatment for prostate cancer is a common practice worldwide to allow diagnosis, prognostication, and treatment planning. However, recent advances in prostate multiparametric magnetic resonance imaging (mpMRI) and prostate-specific membrane antigen (PSMA)-positron emission tomography (PET) have made the possibility of a "biopsy-free" radical prostatectomy, without prior biopsy, closer to reality than before. The biopsy-free approach serves to avoid investigation-related morbidity, health care resources, and time to definitive treatment, but is not without risk. Here we review the literature surrounding the rationale, limitations, and current data.
在全球范围内，前列腺癌根治性治疗前进行前列腺活检是一种常见的做法，以实现诊断、预后评估和治疗规划。然而，前列腺多参数磁共振成像（mpMRI）和前列腺特异性膜抗原（PSMA）正电子发射断层扫描（PET）的最新进展，使得无需事先活检的“无活检”根治性前列腺切除术比以往更接近现实。无活检方法有助于避免与检查相关的发病率、医疗资源消耗以及确定最终治疗的时间，但并非没有风险。在此，我们回顾围绕其基本原理、局限性和当前数据的文献。
