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一项关于胫骨骨折的有限元研究:分析胫骨骨折区域的生物力学状况,为后续治疗提供指导。

A finite element study for tibial fractures: analyze the biomechanical condition of the tibial fracture area to provide guidance for subsequent treatment.

作者信息

Zhang Ke-Rui, Luo Bin, Tu Ju, Li Ya-Qin, Wen Jun, Shen Chang-Yong, Jia Xue-Hai, Deng Yi, Ma Li-Tai, Yang Yi

机构信息

Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.

Department of Orthopedics, Ya'an People's Hospital, Ya'an, China.

出版信息

Front Bioeng Biotechnol. 2025 Jun 20;13:1532207. doi: 10.3389/fbioe.2025.1532207. eCollection 2025.

Abstract

INTRODUCTION

Distal tibial fractures are common fracture sites and usually require surgical treatment to achieve anatomical reduction. Intramedullary nails (IMN) are widely used in orthopedics for stabilizing fractured bones and treating limb deformities. The process of postoperative bone healing is of great significance for patient rehabilitation and can guide subsequent treatment methods. However, the current radiographic techniques used to determine the degree of fusion, such as X-ray, need to be improved in accuracy and have some radiation effects. Several studies suggested that the mechanical load on the fracture area could reflect the bone healing process and evaluated the stability of fracture area. The aim of this study is to investigate the biomechanical changes in the fracture area during bone healing and IMN, and to prepare for the subsequent placement of intelligent stress and displacement sensors based on the changes in stress and displacement, in order to provide guidance for the treatment and rehabilitation of postoperative fractures.

METHODS

Finite element (FE) models representing different healing stages of tibial fractures were developed. All conditions were applied to simulate the stress and strain of the IMN fixation system under normal tibial stress.

RESULTS

The stress at the fracture area on the IMN gradually decreases, while the stress on the callus gradually increases until reaching a stable state at the 12th week after surgery. And the deformation value and the displacement value of the callus decrease and stabilize over time. Based on the changes in stress at the fracture area of the IMN and the displacement value of the callus, we can place a stress sensor at the fracture area of the IMN and a displacement sensor at the callus area.

CONCLUSION

This study utilized FE analysis to evaluate stress, deformation and displacement between the IMN and bone during the healing process of tibial fractures in four stages. By combining these aspects, the degree of bone healing can be assessed. This research enables orthopedic doctors to monitor the progression of fracture healing without relying solely on imaging examinations. Furthermore, it aids in guiding patients to undergo appropriate rehabilitation training for better recovery.

摘要

引言

胫骨干远端骨折是常见的骨折部位,通常需要手术治疗以实现解剖复位。髓内钉(IMN)在骨科中广泛用于稳定骨折骨骼和治疗肢体畸形。术后骨愈合过程对患者康复具有重要意义,并可指导后续治疗方法。然而,当前用于确定融合程度的影像学技术,如X射线,在准确性方面需要改进,并且存在一些辐射影响。多项研究表明,骨折区域的机械负荷可以反映骨愈合过程并评估骨折区域的稳定性。本研究的目的是研究骨愈合和髓内钉植入过程中骨折区域的生物力学变化,并根据应力和位移的变化为后续智能应力和位移传感器的放置做准备,以便为术后骨折的治疗和康复提供指导。

方法

建立了代表胫骨骨折不同愈合阶段的有限元(FE)模型。应用所有条件来模拟正常胫骨应力下髓内钉固定系统的应力和应变。

结果

髓内钉上骨折区域的应力逐渐降低,而骨痂上的应力逐渐增加,直至术后第12周达到稳定状态。并且骨痂的变形值和位移值随时间下降并趋于稳定。基于髓内钉骨折区域的应力变化和骨痂的位移值,我们可以在髓内钉骨折区域放置一个应力传感器,在骨痂区域放置一个位移传感器。

结论

本研究利用有限元分析评估了胫骨骨折愈合过程中四个阶段髓内钉与骨骼之间的应力、变形和位移。通过综合这些方面,可以评估骨愈合程度。这项研究使骨科医生能够在不单纯依赖影像学检查的情况下监测骨折愈合进程。此外,它有助于指导患者进行适当的康复训练以实现更好的恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/033a/12226590/6a5bb658e897/fbioe-13-1532207-g001.jpg

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