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Shock in the post-operative ICU: the etomidate enigma.

作者信息

Viswanath Renjith, Pb Sryma, S Krishnendu

机构信息

Department of Anaesthesiology, PSG Institute of Medical Sciences and Research, Coimbatore, India.

Department of Pulmonary, Critical Care and Sleep Medicine, PSG Institute of Medical Sciences and Research, Coimbatore, India.

出版信息

Anaesthesiol Intensive Ther. 2025 Jul 4;57(1):136-138. doi: 10.5114/ait/200293.

DOI:10.5114/ait/200293
PMID:40621874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12329495/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9476/12329495/ccb58fbcf229/AIT-57-200293-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9476/12329495/ccb58fbcf229/AIT-57-200293-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9476/12329495/ccb58fbcf229/AIT-57-200293-g001.jpg

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Shock in the post-operative ICU: the etomidate enigma.术后重症监护病房中的休克：依托咪酯之谜。
Anaesthesiol Intensive Ther. 2025 Jul 4;57(1):136-138. doi: 10.5114/ait/200293.
2
Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients.在危重症患者中，依托咪酯单次诱导剂量与其他诱导剂用于气管插管的比较。
Cochrane Database Syst Rev. 2015 Jan 8;1(1):CD010225. doi: 10.1002/14651858.CD010225.pub2.
3
The effect between etomidate and ketamine on peri-intubation hypotension in elderly patients in the emergency department.依托咪酯与氯胺酮对急诊科老年患者插管期低血压的影响。
Am J Emerg Med. 2025 Sep;95:41-48. doi: 10.1016/j.ajem.2025.05.021. Epub 2025 May 16.
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Ann Emerg Med. 2010 Aug;56(2):105-13.e5. doi: 10.1016/j.annemergmed.2010.01.030. Epub 2010 Mar 25.
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本文引用的文献

1
Etomidate as an induction agent for endotracheal intubation in critically ill patients: A meta-analysis of randomized trials.依托咪酯作为危重症患者经气管插管诱导剂的效果：一项随机试验的荟萃分析。
J Crit Care. 2023 Oct;77:154317. doi: 10.1016/j.jcrc.2023.154317. Epub 2023 Apr 29.
2
Clinical outcomes after a single induction dose of etomidate versus ketamine for emergency department sepsis intubation: a randomized controlled trial.依托咪酯与氯胺酮单次诱导用于急诊脓毒症患者插管的临床结局：一项随机对照试验。
Sci Rep. 2023 Apr 19;13(1):6362. doi: 10.1038/s41598-023-33679-x.
3
Etomidate versus propofol for sedation in gastrointestinal endoscopy: A systematic review and meta-analysis of outcomes.
依托咪酯与丙泊酚用于胃肠内镜检查镇静：结局的系统评价和荟萃分析。
Medicine (Baltimore). 2023 Feb 10;102(6):e32876. doi: 10.1097/MD.0000000000032876.
4
Relative Adrenal Insufficiency Is Associated With Prolonged Postoperative Hemodynamic Instability.相对肾上腺功能不全与术后血流动力学不稳定时间延长有关。
Ann Thorac Surg. 2018 Sep;106(3):702-707. doi: 10.1016/j.athoracsur.2018.04.014. Epub 2018 May 8.
5
A randomized clinical trial comparing hemodynamic responses to ketamine-propofol combination (ketofol) versus etomidate during anesthesia induction in patients with left ventricular dysfunction undergoing coronary artery bypass graft surgery.一项随机临床试验，比较左心室功能不全患者在接受冠状动脉搭桥手术时，麻醉诱导期氯胺酮 - 丙泊酚合剂（氯胺酚）与依托咪酯的血流动力学反应。
Arch Med Sci. 2017 Aug;13(5):1102-1110. doi: 10.5114/aoms.2016.63193. Epub 2016 Oct 25.
6
Adrenal insufficiency - recognition and management.肾上腺功能不全——识别与管理。
Clin Med (Lond). 2017 Jun;17(3):258-262. doi: 10.7861/clinmedicine.17-3-258.
7
A comparative study between propofol and etomidate in patients under general anesthesia.丙泊酚与依托咪酯用于全身麻醉患者的对比研究。
Braz J Anesthesiol. 2016 May-Jun;66(3):237-41. doi: 10.1016/j.bjane.2014.10.005. Epub 2015 May 12.
8
Etomidate in sepsis: understanding the dilemma.脓毒症中的依托咪酯：理解这一困境。
J Thorac Dis. 2015 Oct;7(10):1699-701. doi: 10.3978/j.issn.2072-1439.2015.10.21.
9
Single-dose etomidate does not increase mortality in patients with sepsis: a systematic review and meta-analysis of randomized controlled trials and observational studies.单剂量依托咪酯不会增加脓毒症患者的死亡率：一项对随机对照试验和观察性研究的系统评价与荟萃分析。
Chest. 2015 Feb;147(2):335-346. doi: 10.1378/chest.14-1012.
10
Etomidate use and postoperative outcomes among cardiac surgery patients.依托咪酯的使用与心脏手术患者的术后转归。
Anesthesiology. 2014 Mar;120(3):579-89. doi: 10.1097/ALN.0000000000000087.