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艾迪生病的临床表现、生长及青春期发育

Clinical presentation, growth, and pubertal development in Addison's disease.

作者信息

Grant D B, Barnes N D, Moncrieff M W, Savage M O

出版信息

Arch Dis Child. 1985 Oct;60(10):925-8. doi: 10.1136/adc.60.10.925.

Abstract

The clinical course of eight boys and six girls with Addison's disease has been reviewed. Adrenal antibodies were found in five boys and five girls, and four children showed clinical evidence of other autoimmune disease (hypoparathyroidism (three); diabetes (one)). The presentation was insidious in 12 children but acute in two. On treatment, linear growth was normal and, with the exception of one girl with theca cell antibodies, pubertal development proceeded normally in the older patients.

摘要

对8名患有艾迪生病的男孩和6名患有艾迪生病的女孩的临床病程进行了回顾。在5名男孩和5名女孩中发现了肾上腺抗体,4名儿童有其他自身免疫性疾病的临床证据(甲状旁腺功能减退症(3例);糖尿病(1例))。12名儿童的症状隐匿,但2名儿童症状急性发作。治疗后,线性生长正常,除一名患有卵泡膜细胞抗体的女孩外,年龄较大的患者青春期发育正常。

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本文引用的文献

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Androgens in pubertal males with Addison's disease.
J Clin Endocrinol Metab. 1980 Oct;51(4):925-9. doi: 10.1210/jcem-51-4-925.
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Addison's disease--clinical studies. A report fo 108 cases.艾迪生病——临床研究。108例报告。
Acta Endocrinol (Copenh). 1974 May;76(1):127-41. doi: 10.1530/acta.0.0760127.
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Familial glucocorticoid insufficiency.
J Pediatr. 1973 May;82(5):821-6. doi: 10.1016/s0022-3476(73)80073-3.
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Hereditary adrenocortical unresponsiveness to adrenocorticotropic hormone.
J Pediatr. 1972 Oct;81(4):726-36. doi: 10.1016/s0022-3476(72)80093-3.

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