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美国艾滋病毒感染者中与抑郁症治疗使用相关的社会人口学和临床因素:一项基于电子健康记录的队列研究。

Sociodemographic and clinical factors associated with use of depression treatment among people with HIV in the United States: An electronic health records-based cohort study.

作者信息

Metz Verena E, Kline-Simon Andrea H, Levine Tory, Sarovar Varada, Lea Alexandra, Van Doren Natalia, Sterling Stacy A, Silverberg Michael J, Satre Derek D

机构信息

Kaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.

Kaiser Permanente Northern California, Division of Research, Pleasanton, CA, United States of America.

出版信息

J Affect Disord. 2025 Jul 5;390:119815. doi: 10.1016/j.jad.2025.119815.

Abstract

BACKGROUND

Depression is highly prevalent among people with HIV (PWH), and treatment is critical. We examined associations between sociodemographic and clinical characteristics, focusing on alcohol use and smoking, with use of depression treatment.

METHODS

Electronic health record data from an integrated healthcare system in Northern California were used to identify PWH who had a primary care visit (index) between 1/1/2014-12/31/2020 and a depression diagnosis within 6 months of the index date. Outcomes included separate indicators for outpatient mental health (MH) encounters and antidepressant prescription fills in the year post index.

RESULTS

Among 3078 PWH, 24.7 % (761) had a depression diagnosis; of those, 52.6 % were aged 50+, 10.5 % female, 56.1 % White, 36.4 % reported alcohol use in the past 3 months and 18.7 % reported current smoking. Seventy-six percent used depression treatment services (antidepressants [68 %] and outpatient MH [35 %]). Patients aged 50-59 years (OR = 0.52, CI = 0.34, 0.80) and 60+ years (OR = 0.27, CI = 0.14, 0.50) were less likely to have outpatient MH encounters compared to patients ≤40 years. Compared to White patients, Black (OR = 0.37, CI = 0.23, 0.59) and Hispanic (OR = 0.48, CI = 0.31, 0.75) patients were less likely to have antidepressant prescription fills, and Black (OR = 0.47, CI = 0.28, 0.77), Hispanic (OR = 0.58, CI = 0.35, 0.94) and Asian (OR = 0.48, CI = 0.25, 0.93) patients were less likely to use any depression treatment. Neither alcohol use nor smoking were associated with depression treatment.

CONCLUSIONS

We found substantial demographic disparities in use of depression treatment services among PWH and depression. Facilitating access to mental health care for older and racial and ethnic minority patients should be prioritized.

摘要

背景

抑郁症在艾滋病毒感染者(PWH)中高度流行,治疗至关重要。我们研究了社会人口统计学和临床特征(重点是饮酒和吸烟)与抑郁症治疗使用之间的关联。

方法

使用来自北加利福尼亚综合医疗系统的电子健康记录数据,以识别在2014年1月1日至2020年12月31日期间进行过初级保健就诊(索引)且在索引日期后6个月内被诊断出患有抑郁症的PWH。结果包括索引后一年中门诊心理健康(MH)就诊和抗抑郁药处方配药的单独指标。

结果

在3078名PWH中,24.7%(761名)被诊断出患有抑郁症;其中,52.6%年龄在50岁以上,10.5%为女性,56.1%为白人,36.4%报告在过去3个月内饮酒,18.7%报告目前吸烟。76%的人使用了抑郁症治疗服务(抗抑郁药[68%]和门诊MH[35%])。与年龄≤40岁的患者相比,50 - 59岁(OR = 0.52,CI = 0.34,0.80)和60岁以上(OR = 0.27,CI = 0.14,0.50)的患者进行门诊MH就诊的可能性较小。与白人患者相比,黑人(OR = 0.37,CI = 0.23,0.59)和西班牙裔(OR = 0.48,CI = 0.31,0.75)患者获得抗抑郁药处方配药的可能性较小,而黑人(OR = 0.47,CI = 0.28,0.77)、西班牙裔(OR = 0.58,CI = 0.35,0.94)和亚洲(OR = 0.48,CI = 0.25,0.93)患者使用任何抑郁症治疗的可能性较小。饮酒和吸烟均与抑郁症治疗无关。

结论

我们发现PWH在抑郁症治疗服务使用方面存在显著的人口统计学差异。应优先促进老年患者以及种族和族裔少数群体患者获得心理健康护理。

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