Zhonghua Xue Ye Xue Za Zhi. 2025 May 14;46(5):402-409. doi: 10.3760/cma.j.cn121090-20250112-00024.
The number of immunocompromised individuals in China is rapidly increasing, and the incidence of cytomegalovirus (CMV) infection in this population is significantly higher than in the general population, severely affecting their quality of life and prognosis. Currently, a standardized diagnostic and treatment system for refractory/resistant CMV infections in immunocompromised populations is lacking. Based on domestic and international data on the epidemiology, evidence-based medicine, and clinical research regarding refractory/resistant CMV infections, this consensus formulates recommendations for the diagnosis, treatment, and management of these infections.
中国免疫功能低下人群的数量正在迅速增加，该人群中巨细胞病毒（CMV）感染的发生率显著高于普通人群，严重影响他们的生活质量和预后。目前，免疫功能低下人群难治性/耐药性CMV感染缺乏标准化的诊断和治疗体系。基于国内外关于难治性/耐药性CMV感染的流行病学、循证医学及临床研究数据，本共识制定了这些感染的诊断、治疗及管理建议。
