Dolan J G, Mushlin A I
Arch Intern Med. 1985 Nov;145(11):2085-8.
We examined the clinical utility of routine admission laboratory testing for medical disorders in 250 psychiatric inpatients by using clinical criteria to classify laboratory abnormalities as true- or false-positive results. The mean number of tests per patient was 27.7. The mean percentage of true-positive results was 1.8%; the mean predictive value was 12%. When three clinically defined subgroups were examined, both measures of test performance varied in direct proportion to the pretest probability of medical disease. Eleven patients (4%) had important medical problems discovered through routine laboratory testing. A testing battery consisting of nine tests in women and 13 in men would have identified all of these patients. Our results suggest that extensive, routine testing for medical disorders in this setting is unnecessary and that more efficient and accurate testing strategies, based on clinical information, can and should be developed.
我们通过使用临床标准将实验室异常结果分类为真阳性或假阳性,研究了250名精神科住院患者常规入院实验室检查对内科疾病的临床实用性。每位患者的平均检查次数为27.7次。真阳性结果的平均百分比为1.8%;平均预测值为12%。当检查三个临床定义的亚组时,两项检查性能指标均与内科疾病的预测试概率成正比。通过常规实验室检查发现11名患者(4%)存在重要内科问题。由9项针对女性和13项针对男性的检查组成的一套检查本可以识别出所有这些患者。我们的结果表明,在此情况下对内科疾病进行广泛的常规检查是不必要的,并且可以而且应该制定基于临床信息的更高效、准确的检查策略。