Neimark Eli, Eremenko Ron, Braudo Sharon, Reitblat Olga, Kleinmann Guy
J Refract Surg. 2025 Jul;41(7):e662-e666. doi: 10.3928/1081597X-20250520-03. Epub 2025 Jul 1.
To evaluate the importance of the anterior chamber depth (ACD), lens thickness (LT), and white-to-white distance (WTW) in predicting the final postoperative refraction using modern formulas.
This was a retrospective study of 140 consecutive eyes that underwent cataract surgery at the Department of Ophthalmology, Edith Wolfson Medical Centre, Holon, Israel. The Barrett Universal II (BUII), Kane, and Hill-RBF 3.0 formulas were calculated for each eye with all combinations of omitting ACD, LT, and WTW, as possible by each formula. Lens constant optimizations were executed. The results were compared to the postoperative refraction.
For the BUII formula, the ACD only variation exhibited a statistically significant increase in mean absolute deviation (MAD) (0.024 diopters [D], = .010) and standard deviation of prediction error (SD-PE) (0.022, = .002) compared with BUII using all parameters, whereas no other variations showed statistically significant differences in MAD or SD-PE. For the Hill-RBF 3.0 formula, both the ACD only (0.012 D, < .001) and ACD+WTW (0.009 D, = .016) variations demonstrated a statistically significant increase in MAD, although no statistically significant differences were observed in SD-PE. For the Kane formula, excluding the LT parameter resulted in a statistically significant increase in MAD (0.020 D, = .034), whereas the increase in SD-PE (0.020, = .266) was not statistically significant.
The BUII, Kane, and Hill-RBF 3.0 formulas demonstrated statistically significant, but not clinically meaningful, differences in SD-PE and MAD when ACD, LT, and WTW were excluded in normal biometric eyes. Further research involving eyes with atypical biometric characteristics is warranted to enhance refractive accuracy and minimize outliers. .
使用现代公式评估前房深度（ACD）、晶状体厚度（LT）和白对白距离（WTW）在预测最终术后屈光方面的重要性。
这是一项对以色列霍隆伊迪丝·沃尔夫森医疗中心眼科连续140只接受白内障手术的眼睛进行的回顾性研究。针对每只眼睛，通过每个公式尽可能地对省略ACD、LT和WTW的所有组合计算巴雷特通用II（BUII）、凯恩和希尔 - RBF 3.0公式。进行了晶状体常数优化。将结果与术后屈光进行比较。
对于BUII公式，与使用所有参数的BUII相比，仅ACD变化显示平均绝对偏差（MAD）有统计学显著增加（0.024屈光度[D]，P = 0.010）以及预测误差标准差（SD - PE）有统计学显著增加（0.022，P = 0.002），而其他变化在MAD或SD - PE方面未显示统计学显著差异。对于希尔 - RBF 3.0公式，仅ACD（0.012 D，P < 0.001）和ACD + WTW（0.009 D，P = 0.016）变化均显示MAD有统计学显著增加，尽管在SD - PE方面未观察到统计学显著差异。对于凯恩公式，排除LT参数导致MAD有统计学显著增加（0.020 D，P = 0.034），而SD - PE的增加（0.020，P = 0.266）无统计学显著意义。
在正常生物测量的眼睛中，当排除ACD、LT和WTW时，BUII、凯恩和希尔 - RBF 3.0公式在SD - PE和MAD方面显示出统计学显著但无临床意义的差异。有必要对具有非典型生物测量特征的眼睛进行进一步研究，以提高屈光准确性并尽量减少异常值。
