Lim Perry, Clark Aaron J, Katz Austen D, Toobaie Asra, Deviren Vedat, Ames Christopher P, Theologis Alekos A
Department of Orthopedic Surgery, University of California - San Francisco, 500 Parnassus Ave, MUW 3 Floor, San Francisco, CA, 94143, USA.
Department of Neurological Surgery, UCSF, San Francisco, CA, USA.
Spine Deform. 2025 Jul 8. doi: 10.1007/s43390-025-01141-9.
To explore the impact of different lumbar pedicle subtraction osteotomy (L-PSO) levels on Global Alignment and Proportion (GAP) scores.
Adults at a single center who underwent lumbar PSOs with revision instrumentation [thoracolumbar junction (T9-L1) to pelvis] and a minimum 2-year follow-up were reviewed. The patients were divided by level of PSO (L2, L3, L4, and L5) and compared with respect to demographic and surgical data, sagittal parameters, GAP scores, and mechanical complications requiring revision operations.
152 patients (average age 64.4 ± 10.6 years, average follow-up 9.0 ± 4.1 years) were included for analysis. L3 (40.8%) and L4 (45.4%) PSOs were more common than L2 (4.6%) and L5 (9.2%) PSOs. Average pre-op GAP scores (9.8 ± 2.8) were similar and improved significantly for all L-PSO levels, although post-op GAP scores (7.1 ± 2.2) remained "disproportioned" for all L-PSO levels. Post-op Lumbar Distribution Index (LDI) scores were significantly better for lower PSOs (L4 + L5) given better improvement of L4-S1 lordosis. The revisions for mechanical failures were higher in L2 and L3 PSOs. Average post-op GAP scores were not different for patients who did and did not undergo mechanical failure revisions.
L-PSOs, irrespective of the level, improve GAP scores. While residual disproportionate post-operative alignment was observed for all L-PSO levels, distal PSOs improved L4-S1 lordosis and LDI scores to a greater extent than proximal PSOs. Although more distal lumbar PSOs also had lower rates of revision operations for mechanical complications, other patient and surgical factors also likely played a role in the observed rates of mechanical failures.
探讨不同腰椎椎体截骨术(L-PSO)水平对整体对线和比例(GAP)评分的影响。
回顾了在单一中心接受腰椎PSO并进行翻修内固定术(胸腰段交界区(T9-L1)至骨盆)且至少随访2年的成年人。患者按PSO水平(L2、L3、L4和L5)分组,并就人口统计学和手术数据、矢状面参数、GAP评分以及需要翻修手术的机械并发症进行比较。
纳入152例患者(平均年龄64.4±10.6岁,平均随访9.0±4.1年)进行分析。L3(40.8%)和L4(45.4%)PSO比L2(4.6%)和L5(9.2%)PSO更常见。所有L-PSO水平术前平均GAP评分(9.8±2.8)相似且均显著改善,尽管所有L-PSO水平术后GAP评分(7.1±2.2)仍“不成比例”。由于L4-S1前凸改善更好,低位PSO(L4+L5)术后腰椎分布指数(LDI)评分显著更好。L2和L3 PSO的机械故障翻修率更高。进行和未进行机械故障翻修的患者术后平均GAP评分无差异。
L-PSO无论水平如何,均能改善GAP评分。虽然所有L-PSO水平术后均观察到残留的不成比例对线,但低位PSO比高位PSO在更大程度上改善了L4-S1前凸和LDI评分。尽管低位腰椎PSO因机械并发症进行翻修手术的发生率也较低,但其他患者和手术因素可能也在观察到的机械故障发生率中起作用。