Park Sena, Lee Daniel, Kim Tae Jun, Kitzing Yu Xuan, Lee Peter J
Department of General Surgery, Manning Base Hospital, Taree, New South Wales, Australia.
Department of Colorectal Surgery, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Colorectal Dis. 2025 Jul;27(7):e70160. doi: 10.1111/codi.70160.
Parastomal hernia (PSH) is a common complication of stoma formation, with an incidence of up to 80%. PSH carries significant morbidity associated with pain and physical function, emphasizing the importance of its prevention. The aim of this work is to review those patients who underwent prophylactic placement of GORE® BIO-A® (Delaware, USA) mesh in accordance with IDEAL Stage 2a and its effectiveness in preventing PSH.
A retrospective case series study was performed at Royal Prince Alfred Hospital, a quaternary centre in Sydney, Australia. Twenty-four patients who underwent prophylactic placement of GORE® BIO-A® mesh at the time of stoma formation by a single surgeon between 2014 and 2022 were included. The presence of PSH on their most current imaging on CT was assessed by a Fellow of the Royal Australasian and New Zealand College of Radiologists.
Out of 24 patients, four (16.7%) had radiological evidence of PSH identified on their progress CT scan. The mean age of all patients was 63 years and all patients had permanent end colostomies. The mean duration between the operation and latest CT scan was 30 months.
The use of GORE® BIO-A® at the time of stoma formation may reduce the rate of PSH. The significantly low incidence of PSH identified in this study indicates that GORE BIO-A mesh has the potential to reduce the risk of PSH formation and its complications. The current IDEAL Stage 2a provides the opportunity for further research with this novel mesh and the technique of prevention of PSH.
造口旁疝(PSH)是造口形成的常见并发症,发病率高达80%。PSH会引发与疼痛和身体功能相关的显著发病率,凸显了预防的重要性。本研究旨在回顾那些根据IDEAL 2a期标准接受了GORE® BIO-A®(美国特拉华州)补片预防性植入的患者及其在预防PSH方面的有效性。
在澳大利亚悉尼的一家四级中心——皇家阿尔弗雷德王子医院进行了一项回顾性病例系列研究。纳入了2014年至2022年间由一名外科医生在造口形成时接受GORE® BIO-A®补片预防性植入的24例患者。由澳大利亚和新西兰皇家放射学院的一名研究员评估他们最新的CT影像上PSH的情况。
在24例患者中,4例(16.7%)在其进展期CT扫描上有PSH的影像学证据。所有患者的平均年龄为63岁,均为永久性乙状结肠造口。手术与最新CT扫描之间的平均时间为30个月。
在造口形成时使用GORE® BIO-A®可能会降低PSH的发生率。本研究中PSH的低发病率表明GORE BIO-A补片有降低PSH形成风险及其并发症的潜力。当前的IDEAL 2a期为进一步研究这种新型补片及PSH预防技术提供了机会。