[各种血液系统疾病中的血小板腺苷脱氨酶]
[Platelet adenosine desaminase in various hematological diseases].
作者信息
Sokovnina Ia M, Pestina T I, Chizhova A I, Tentsova I A, Lagutina N Ia
出版信息
Vopr Med Khim. 1985 May-Jun;31(3):26-30.
Activity of adenosine deaminase (EC 3.5.4.4) was studied in thrombocytes of donors and patients with various hematological diseases. The enzymatic activity was decreased in acute leukemia, chronic myeloleukemia, chronic leukemia and blast transformation myeloma, microspherocytic and hypoplastic anemias. Variable level of the activity was observed in chronic lympholeukemia and non-Hodgkin disease. In all the diseases studied functions of thrombocytes were altered after treatment with various aggregating agents (ADP, thrombin, collagen, adrenaline, ristomycin).
研究了腺苷脱氨酶（EC 3.5.4.4）在献血者以及患有各种血液系统疾病患者血小板中的活性。急性白血病、慢性粒细胞白血病、慢性白血病和原始细胞转化型骨髓瘤、小球形红细胞性贫血和再生障碍性贫血患者的酶活性降低。在慢性淋巴细胞白血病和非霍奇金病患者中观察到活性水平有所不同。在所有研究的疾病中，用各种聚集剂（二磷酸腺苷、凝血酶、胶原蛋白、肾上腺素、瑞斯托霉素）处理后血小板功能均发生改变。
Zotero 插件