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[人类主动脉的细胞组成和生化特性]

[Cellular composition and biochemical characteristics of the human aorta].

作者信息

Andreeva E R, Tertov V V, Mukhin D N, Orekhov A N

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1985;8(2):63-71.

PMID:4063084
Abstract

Development of atherosclerotic lesions in the human aortic intima has been studied using morphological and biochemical methods. It is shown that the sublayers of the human aortic intima are involved in the atherosclerotic processes in different degree. Such manifestation of atherosclerosis as lipid and collagen take up and intimal thickness are especially connected with juxtluminal layer of the intima. Stellate cells (one of the 4 morphological types in the intima) are most closely correlated with these processes. The problems of the origin and possible role of the intima cells in the atherosclerosis are discussed.

摘要

利用形态学和生物化学方法对人类主动脉内膜动脉粥样硬化病变的发展进行了研究。结果表明,人类主动脉内膜的各亚层不同程度地参与了动脉粥样硬化过程。动脉粥样硬化的脂质和胶原蛋白摄取以及内膜厚度等表现尤其与内膜的近腔层有关。星状细胞(内膜中4种形态类型之一)与这些过程的相关性最为密切。本文讨论了内膜细胞在动脉粥样硬化中的起源问题及其可能的作用。

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