Isa Hideki, Ushioda Ryohei, Takahashi Baku, Yoongtong Dit, Sakboon Boonsap, Cheewinmethasiri Jaroen, Kamiya Hiroyuki, Arayawudhikul Nuttapon
Cardiovascular and Thoracic Surgery Unit, Department of Surgery, Lampang Hospital, Lampang, Thailand.
Department of Cardiac Surgery, Asahikawa Medical University, Asahikawa, Japan.
JTCVS Open. 2025 May 2;25:134-142. doi: 10.1016/j.xjon.2025.04.009. eCollection 2025 Jun.
This study compared the I-composite graft comprising the right internal thoracic artery and radial artery with the gastroepiploic artery in off-pump coronary artery bypass grafting for severe right coronary artery stenosis.
This study included 78 and 141 patients who underwent right internal thoracic artery-radial artery and gastroepiploic artery grafting, respectively, for off-pump coronary artery bypass grafting between April 2011 and June 2024. Propensity score matching was conducted, and postoperative outpatient follow-up was performed.
Propensity score matching resulted in 65 patients in each group. Preoperative characteristics, operative time, and the number of arterial revascularizations and distal anastomoses did not differ significantly between the groups. However, more graft conduits were used in the right internal thoracic artery-radial artery group. Short-term postoperative outcomes were similar, except for a significantly higher early extubation rate in the right internal thoracic artery-radial artery group. During a median follow-up of 5.0 years, overall survival did not differ significantly between the groups. However, the gastroepiploic artery group had a significantly lower long-term freedom from major adverse cardiac and cerebrovascular events, particularly heart failure requiring hospitalization. Multivariate analysis identified a history of peripheral arterial disease as a significant risk factor for overall mortality, whereas the type of right coronary artery graft was not.
Using the gastroepiploic artery as a direct conduit for severe right coronary artery stenosis appears to be a promising option when selecting an arterial graft, particularly in improving major adverse cardiac or cerebrovascular events-free survival.
本研究比较了在非体外循环冠状动脉搭桥术中,由右胸廓内动脉和桡动脉组成的I型复合移植物与胃网膜动脉用于严重右冠状动脉狭窄的情况。
本研究纳入了2011年4月至2024年6月期间分别接受右胸廓内动脉-桡动脉和胃网膜动脉移植进行非体外循环冠状动脉搭桥术的78例和141例患者。进行倾向评分匹配,并对术后门诊患者进行随访。
倾向评分匹配后每组各有65例患者。术前特征、手术时间、动脉血运重建数量和远端吻合数量在两组之间无显著差异。然而,右胸廓内动脉-桡动脉组使用的移植管道更多。术后短期结果相似,除了右胸廓内动脉-桡动脉组的早期拔管率显著更高。在中位随访5.0年期间,两组的总生存率无显著差异。然而,胃网膜动脉组的长期无重大不良心脑血管事件生存率显著更低,尤其是需要住院治疗的心力衰竭。多因素分析确定外周动脉疾病史是总死亡率的显著危险因素,而右冠状动脉移植物类型不是。
当选择动脉移植物时,使用胃网膜动脉作为严重右冠状动脉狭窄的直接管道似乎是一个有前景的选择,特别是在提高无重大不良心脑血管事件生存率方面。