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机器人辅助原位双侧胸廓内动脉多支冠状动脉搭桥术的早期结果及随访:单中心221例患者报告

Early outcomes and follow-up of robotic-assisted multivessel coronary artery bypass with in situ bilateral internal thoracic artery: Report of 221 patients in a single center.

作者信息

Fu Yuanhao, Hong Yi, Ding Tong, Meng Luyu, Gong Yichen, Wu Song, Ling Yunpeng

机构信息

Department of Cardiac Surgery, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.

Department of Cardiac Surgery, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.

出版信息

J Thorac Cardiovasc Surg. 2025 Jun 16. doi: 10.1016/j.jtcvs.2025.06.008.

Abstract

OBJECTIVE

Robotic-assisted harvesting of bilateral internal thoracic arteries offers significant advantages, and bilateral internal thoracic arteries grafting improves outcomes. This study retrospectively examined early clinical outcomes and follow-ups of patients who underwent robotic-assisted coronary artery bypass grafting with in situ bilateral internal thoracic arteries as a standardized technique in a single center.

METHODS

Between April 2021 and June 2024, 369 consecutive patients underwent robotic-assisted coronary artery bypass grafting at our center, including 221 (59.9%) with in situ bilateral internal thoracic arteries. Skeletonized bilateral internal thoracic arteries harvesting was performed using a robotic system, followed by off-pump hand-sewn distal anastomoses accessed via a 4- to 6-cm left thoracotomy. A radial artery was harvested in 63 patients (28.5%) as a third conduit, forming a composite I-graft. Angiography was performed before discharge to confirm graft patency. The primary end points were major adverse cardiac/cerebrovascular events and all-cause mortality.

RESULTS

Among 221 patients, the number of grafts was 2, 3, and 4 or more vessels in 124 patients (56.1%), 64 patients (29.0%), and 33 patients (14.9%), respectively. Hybrid therapy was performed in 9 (4.1%) cases. There was 1 (0.5%) conversion to peripheral cardiopulmonary bypass, no sternotomy conversions, and 1 (0.5%) postoperative death. Perioperative morbidity included 12 (5.5%) transfusions and 10 (4.5%) reexplorations for bleeding or revascularization. The postoperative graft angiography was performed on 216 patients (97.7%) and revealed an overall graft patency rate of 97.1% (545/561). The 12-month survival was 98.5%, with major adverse cardiac/cerebrovascular event-free survival at 97.1%.

CONCLUSIONS

Robotic-assisted coronary artery bypass grafting with in situ bilateral internal thoracic arteries is a safe, effective, and minimally invasive alternative to sternotomy coronary artery bypass grafting, achieving total arterial revascularization and potentially improving long-term survival.

摘要

目的

机器人辅助双侧胸廓内动脉获取具有显著优势,双侧胸廓内动脉移植可改善治疗效果。本研究回顾性分析了在单一中心采用标准化技术行机器人辅助冠状动脉旁路移植术并使用原位双侧胸廓内动脉的患者的早期临床结局和随访情况。

方法

2021年4月至2024年6月期间,369例患者在本中心接受了机器人辅助冠状动脉旁路移植术,其中221例(59.9%)采用原位双侧胸廓内动脉。使用机器人系统进行双侧胸廓内动脉骨骼化获取,然后通过4至6厘米的左胸切口进行非体外循环下手工缝合远端吻合。63例患者(28.5%)获取桡动脉作为第三条移植血管,形成复合I型移植物。出院前进行血管造影以确认移植血管通畅。主要终点为主要不良心脑血管事件和全因死亡率。

结果

221例患者中,分别有124例(56.1%)、64例(29.0%)和33例(14.9%)移植血管数量为2、3和4支及以上。9例(4.1%)患者接受了杂交治疗。有1例(0.5%)转为外周体外循环,无胸骨切开术转换,1例(0.5%)患者术后死亡。围手术期并发症包括12例(5.5%)输血和10例(4.5%)因出血或血运重建再次手术。216例患者(97.7%)术后进行了移植血管造影,总体移植血管通畅率为97.1%(545/561)。12个月生存率为98.5%,主要不良心脑血管事件无事件生存率为97.1%。

结论

机器人辅助冠状动脉旁路移植术联合原位双侧胸廓内动脉是胸骨切开冠状动脉旁路移植术的一种安全、有效且微创的替代方法,可实现完全动脉血运重建并可能改善长期生存。

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