Bossola Maurizio, Angioletti Laura, Trotta Alessia, Tommolini Valeria, Giovanni Marta Di, Mariani Ilaria, Stasio Enrico Di, Balconi Michela
Servizio Emodialisi, Università Cattolica del Sacro Cuore, Rome, Italy.
Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
J Ren Care. 2025 Sep;51(3):e70026. doi: 10.1111/jorc.70026.
Depression is common in patients with chronic kidney disease on maintenance hemodialysis. However, depression prevalence and associated variables have been less studied in maintenance hemodialysis patients older than 65 years old.
This study aimed to define the prevalence of depression and the associated variables in older patients on maintenance hemodialysis.
This is a cross-sectional study.
Participants included 197 older patients on maintenance hemodialysis (age range 65-80) recruited between September 2023 to September 2024 in Italy.
Depression levels were measured with the Beck Depression Inventory II and perceived stress levels with the Perceived Stress Scale. We also collected clinical and laboratory variables.
Of 197 patients, 130 patients (66%) had Beck Depression Inventory < 14 and 67 (34%) had Beck Depression Inventory ≥ 14. The two groups differed for age, sex, dialytic age, activity of daily living and instrumental activity of daily living scores, Body Mass Index, post-dialysis fatigue, dialysis recovery time, Perceived Stress Scale score, and serum creatinine. At the logistic regression analysis, the Beck Depression Inventory score was independently associated with female sex, post-dialysis fatigue, low IADL, and Perceived Stress Scale score. Post-dialysis fatigue intensity, duration, and frequency and the post-dialysis fatigue sum were significantly higher in patients with Beck Depression Inventory ≥ 14 than in those with Beck Depression Inventory < 14. The correlation between Beck Depression Inventory and Perceived Stress Scale was statistically significant. Then, we stratified patients according to the score of the Cohen's Perceived Stress Scale into three groups: low stress (0-13), moderate stress (14-26), and severe stress (27-40). Patients with Beck Depression Inventory≥ 14 had a higher frequency of severe perceived stress.
Beck Depression Inventory score was independently associated with female sex, instrumental activity of daily living and Perceived Stress Scale score in older patients on maintenance hemodialysis.
抑郁症在维持性血液透析的慢性肾脏病患者中很常见。然而，65岁以上维持性血液透析患者的抑郁症患病率及相关变量的研究较少。
本研究旨在确定老年维持性血液透析患者的抑郁症患病率及相关变量。
这是一项横断面研究。
参与者包括2023年9月至2024年9月在意大利招募的197名老年维持性血液透析患者（年龄范围65 - 80岁）。
使用贝克抑郁量表第二版测量抑郁水平，使用感知压力量表测量感知压力水平。我们还收集了临床和实验室变量。
197名患者中，130名患者（66%）贝克抑郁量表得分<14，67名（34%）贝克抑郁量表得分≥14。两组在年龄、性别、透析龄、日常生活活动和工具性日常生活活动得分、体重指数、透析后疲劳、透析恢复时间、感知压力量表得分和血清肌酐方面存在差异。在逻辑回归分析中，贝克抑郁量表得分与女性性别、透析后疲劳、低工具性日常生活活动能力和感知压力量表得分独立相关。贝克抑郁量表得分≥14的患者透析后疲劳强度、持续时间、频率及透析后疲劳总分显著高于贝克抑郁量表得分<14的患者。贝克抑郁量表与感知压力量表之间的相关性具有统计学意义。然后，我们根据科恩感知压力量表的得分将患者分为三组：低压力（0 - 13）、中度压力（14 - 26）和重度压力（27 - 40）。贝克抑郁量表得分≥14的患者严重感知压力的频率更高。
在老年维持性血液透析患者中，贝克抑郁量表得分与女性性别、工具性日常生活活动能力和感知压力量表得分独立相关。
