Azharudeen Mohamed, V Ravindran, Kt Shahina, Bin Ismail Ikram, Sai E Midhun, P A Jaslin
Department of Oral and Maxillofacial Surgery, Government Dental College, Kozhikode, 673008, India.
Department of Oral and Maxillofacial Surgery, Government Medical College, Manjeri, 676123, India.
Oral Maxillofac Surg. 2025 Jul 9;29(1):133. doi: 10.1007/s10006-025-01429-0.
Maxillomandibular fixation (MMF) serves as a conventional approach for immobilizing jaws in the treatment of maxillofacial fractures. However, intermaxillary fixation poses challenges to nutritional status in the immediate postoperative phase, resulting in the depletion of water, fat, and protein reserves. The objective is to evaluate the variations in total protein and albumin levels at distinct intervals throughout the treatment duration, aiming to elucidate the impact of intermaxillary fixation on nutritional markers.
A total of 144 patients with jaw fractures presenting to the Oral and Maxillofacial Surgery Department of Govt. Dental College, Calicut, necessitating maxillomandibular fixation, were enrolled irrespective of etiology. They were randomly allocated into two groups: the Nutrition Intervention Group (GROUP 1) and the Nutrition Non-intervention Group (GROUP 2). Biochemical parameters including total protein and serum albumin were assessed. Measurements were conducted on the day of MMF initiation, as well as after the 2nd and 4th weeks thereafter.
Significant variations were observed in the protein and albumin levels, with an increase in group 1 and a decrease in group 2 patients following maxillomandibular fixation (MMF).
This study highlights the significant impact of personalized nutritional intervention on total protein and albumin levels in patients undergoing maxillomandibular fixation (MMF) for jaw fractures. Compared to the non-intervention group, those receiving tailored dietary counselling showed marked improvements in both protein and albumin levels. This emphasizes the importance of individualized nutritional support during MMF, essential for tissue repair, immune function, and overall recovery.
颌间固定（MMF）是治疗颌面部骨折时固定颌骨的传统方法。然而，颌间固定在术后即刻会对营养状况造成挑战，导致水、脂肪和蛋白质储备的消耗。目的是评估在整个治疗期间不同时间间隔的总蛋白和白蛋白水平变化，以阐明颌间固定对营养指标的影响。
共有144例因颌骨骨折就诊于卡利卡特政府牙科学院口腔颌面外科且需要进行颌间固定的患者纳入研究，不考虑病因。他们被随机分为两组：营养干预组（第1组）和非营养干预组（第2组）。评估包括总蛋白和血清白蛋白在内的生化参数。在颌间固定开始当天以及此后第2周和第4周后进行测量。
颌间固定（MMF）后，第1组患者的蛋白和白蛋白水平升高，第2组患者的蛋白和白蛋白水平降低，两组之间存在显著差异。
本研究强调了个性化营养干预对因颌骨骨折接受颌间固定（MMF）患者的总蛋白和白蛋白水平有显著影响。与非干预组相比，接受定制饮食咨询的患者在蛋白和白蛋白水平上均有明显改善。这强调了颌间固定期间个性化营养支持的重要性，这对组织修复、免疫功能和整体恢复至关重要。
