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胎盘蛋白12（PP12）：预测小于胎龄儿的一项新检测方法。

Placental protein 12 (PP12): a new test for the prediction of the small-for-gestational-age infant.

作者信息

Howell R J, Perry L A, Choglay N S, Bohn H, Chard T

出版信息

Br J Obstet Gynaecol. 1985 Nov;92(11):1141-4. doi: 10.1111/j.1471-0528.1985.tb03026.x.

DOI:10.1111/j.1471-0528.1985.tb03026.x
PMID:4063231
Abstract

The circulating levels of placental protein 12 (PP12) and placental lactogen (hPL) were measured in 501 women between 36 and 41 weeks gestation. There was a significant positive association between hPL levels and infant birthweight and a significant negative association in the case of PP12 levels. The clinical efficiency of elevated PP12 levels in the prediction of low-birthweight infant at term compared favourably with that of reduced hPL levels.

摘要

对501名妊娠36至41周的女性测定了胎盘蛋白12（PP12）和胎盘催乳素（hPL）的循环水平。hPL水平与婴儿出生体重之间存在显著正相关，而PP12水平则存在显著负相关。足月时PP12水平升高对预测低出生体重儿的临床效能与hPL水平降低的情况相比具有优势。

相似文献

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Placental protein 12 (PP12): a new test for the prediction of the small-for-gestational-age infant.胎盘蛋白12（PP12）：预测小于胎龄儿的一项新检测方法。
Br J Obstet Gynaecol. 1985 Nov;92(11):1141-4. doi: 10.1111/j.1471-0528.1985.tb03026.x.
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Placental proteins 12 and 14 in pre-eclampsia.子痫前期中的胎盘蛋白12和14
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Placental protein 12 (PP12): factors affecting levels in late pregnancy.胎盘蛋白12（PP12）：影响妊娠晚期水平的因素。
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Second- and third-trimester serum levels of placental proteins in preeclampsia and small-for-gestational age pregnancies.子痫前期和小于胎龄儿妊娠中孕晚期胎盘蛋白的血清水平。
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[The determination of human placental lactogen (HPL) for hormonal supervision in late pregnancy].[测定人胎盘催乳素（HPL）用于晚期妊娠的激素监测]
Zentralbl Gynakol. 1976;98(18):1129-36.
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hPL: physiologic and pathophysiologic observations.人胎盘催乳素：生理学和病理生理学观察
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Prediction of small-for-gestational-age neonates: screening by biophysical and biochemical markers at 30-34 weeks.小于胎龄儿的预测：孕30 - 34周时通过生物物理和生化标志物进行筛查。
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Further investigation on the predictive value of human placental lactogen in high-risk pregnancies.人胎盘催乳素在高危妊娠中预测价值的进一步研究。
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Biochemical tests of placental function versus ultrasound assessment of fetal size for stillbirth and small-for-gestational-age infants.胎盘功能生化检测与超声评估胎儿大小对死产及小于胎龄儿的影响
Cochrane Database Syst Rev. 2019 May 14;5(5):CD012245. doi: 10.1002/14651858.CD012245.pub2.
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Insulin-like growth factor axis in pregnancies affected by fetal growth disorders.受胎儿生长障碍影响的妊娠中的胰岛素样生长因子轴。
Clin Epigenetics. 2016 Jan 27;8:11. doi: 10.1186/s13148-016-0178-5. eCollection 2016.
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Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia.
缺氧刺激HepG2细胞中胰岛素样生长因子结合蛋白1（IGFBP-1）基因表达：胎儿缺氧时IGFBP-1表达的一种可能模型。
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10188-93. doi: 10.1073/pnas.95.17.10188.
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Placental protein 14 (PP14) in late pregnancy.
Arch Gynecol. 1986;239(1):27-9. doi: 10.1007/BF02134285.
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Circulating levels of placental protein 12 in complications of first trimester pregnancy.
Arch Gynecol Obstet. 1989;246(4):201-6. doi: 10.1007/BF00934519.
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Circulating levels of placental protein 12 in ectopic pregnancy.
Arch Gynecol Obstet. 1990;247(3):139-53. doi: 10.1007/BF02390863.