Hong Suk-Joon, Vu My H, Vanderbilt Douglas, Yin Larry, Imagawa Karen Kay, Deavenport-Saman Alexis
Division of Developmental-Behavioral Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA.
Biostatistics and Data Analysis Core, Children's Hospital Los Angeles, Los Angeles, CA.
J Dev Behav Pediatr. 2025 Jul 8. doi: 10.1097/DBP.0000000000001395.
Children with higher adverse childhood experiences (ACEs) experience more severe parent-reported attention-deficit/hyperactivity disorder (ADHD). Positive childhood experiences (PCEs) help to build resilience and mitigate the impact of ACEs on ADHD. Prior studies have measured the 2 constructs as independent factors, but no research has examined their combined influence on children with ADHD. The first aim was to categorize children with different levels of parent-reported ADHD severity into classes based on shared characteristics of ACE and PCE promoters. The second aim was to examine the relationship between the classes and ADHD severity.
Participants included children 6 to 17 years with data on the 2019 National Survey of Children's Health ADHD severity questionnaire (n = 19,715; weighted n = 49,149,269). Latent class analysis (LCA) identified subgroups of children experiencing patterns among PCE promoters and ACEs, which were measured as independent variables in an adjusted ordinal regression model to estimate their composite effects on ADHD severity.
Using LCA, one class belonging to children with low ACEs and high PCE promoters (class 1) and another belonging to children with high ACEs and low PCE promoters (class 2) were identified. Class 2 was 2.2 times more likely to have more severe ADHD (aOR 2.2; 95% confidence interval, 1.8-2.6).
Findings suggest ACEs and PCE promoters do not operate independently; children with high ACEs had low PCE promoters and had more severe parent-reported ADHD. Clinicians should consider actively screening for the presence of ACEs and PCEs in all children, especially those with high ADHD severity, and build strong alliances with families.
童年不良经历(ACEs)较多的儿童在家长报告的注意力缺陷多动障碍(ADHD)方面表现更为严重。积极的童年经历(PCEs)有助于培养复原力,并减轻ACEs对ADHD的影响。先前的研究将这两个概念作为独立因素进行测量,但尚无研究考察它们对ADHD儿童的综合影响。第一个目标是根据ACE和PCE促进因素的共同特征,将家长报告的ADHD严重程度不同的儿童分类。第二个目标是研究这些类别与ADHD严重程度之间的关系。
参与者包括6至17岁的儿童,他们有2019年全国儿童健康调查ADHD严重程度问卷的数据(n = 19,715;加权n = 49,149,269)。潜在类别分析(LCA)确定了在PCE促进因素和ACEs中经历特定模式的儿童亚组,这些因素在调整后的有序回归模型中作为自变量进行测量,以估计它们对ADHD严重程度的综合影响。
使用LCA,确定了一类是ACEs低且PCE促进因素高的儿童(第1类),另一类是ACEs高且PCE促进因素低的儿童(第2类)。第2类儿童患更严重ADHD的可能性是第1类的2.2倍(调整后的比值比为2.2;95%置信区间为1.8 - 2.6)。
研究结果表明,ACEs和PCE促进因素并非独立起作用;ACEs高的儿童PCE促进因素低,且家长报告的ADHD更严重。临床医生应考虑积极筛查所有儿童,尤其是ADHD严重程度高的儿童中ACEs和PCEs的存在情况,并与家庭建立紧密的联盟。