Katona C L, Barnes T R
Br J Hosp Med. 1985 Sep;34(3):168-71.
Several pharmacological manoeuvres may be considered when the first attempt at antidepressant treatment fails. The importance of adequate dosage and duration in any treatment trial are emphasized, and the evidence in support of combined antidepressants, lithium-antidepressant combinations, the addition of triiodothyronine or tryptophan, the use of anticonvulsants, and the use of vanadium inactivators, is evaluated.
当首次抗抑郁治疗尝试失败时，可以考虑几种药理学策略。强调了在任何治疗试验中适当剂量和疗程的重要性，并对联合使用抗抑郁药、锂盐与抗抑郁药联合使用、添加三碘甲状腺原氨酸或色氨酸、使用抗惊厥药以及使用钒失活剂的证据进行了评估。
