Sturt E, Shur E
Br J Psychiatry. 1985 Jul;147:44-7. doi: 10.1192/bjp.147.1.44.
Some hypotheses about the cause of schizophrenia are based on the puzzling tendency for mental illness to affect the same sex when two close relatives become psychiatrically ill. Sex-concordance rates were examined in 71 schizophrenic probands, who had at least one first-degree relative suffering from the same disorder, in order to test this tendency in a population of recently admitted patients. No unusual concordance rates were found when unaffected sibs were taken into account and relatives were stratified to take account of possible confounding factors. It would seem premature to construct hypotheses about the aetiology of schizophrenia based on evidence of this type.
关于精神分裂症病因的一些假说，是基于一种令人困惑的倾向：当两个近亲都患上精神疾病时，精神疾病更容易影响同性。为了在一组近期入院的患者群体中检验这种倾向，研究人员对71名精神分裂症先证者进行了性一致率的检查，这些先证者至少有一位一级亲属患有相同疾病。当考虑到未患病的同胞，并对亲属进行分层以考虑可能的混杂因素时，未发现异常的一致率。基于这类证据构建关于精神分裂症病因的假说，似乎为时过早。
