Yuan Hongjun, Yu Hongli, Guan Ying, Wang Wenjing, Yu Qiang, Lu Yinying, Liu Fengyong
Department of Interventional Radiology, The 5th Medical Center of the PLA General Hospital, Beijing 100039, China.
Comprehensive Liver Cancer Center, The 5th Medical Center of the PLA General Hospital, Beijing 100039, China.
ILIVER. 2025 Apr 23;4(2):100164. doi: 10.1016/j.iliver.2025.100164. eCollection 2025 Jun.
The treatment of liver metastases is undergoing a transformation from single-modality therapy to multimodal combination therapy, with local interventional treatments playing an increasingly important role. This review explores the synergistic effects between local interventional therapy and systemic treatment, the reconstruction of interventional therapy indications driven by advances in systemic treatment, and the impact of local interventional therapy on systemic treatment "switching" strategies. Through multidisciplinary collaboration and innovative interventional materials and techniques, local interventional therapy has evolved from a traditional palliative approach to become an essential component in the comprehensive treatment system for liver metastases.
肝转移瘤的治疗正在从单一模式治疗向多模式联合治疗转变，局部介入治疗发挥着越来越重要的作用。本文综述探讨了局部介入治疗与全身治疗之间的协同效应、全身治疗进展推动的介入治疗适应证的重新构建，以及局部介入治疗对全身治疗“转换”策略的影响。通过多学科协作以及创新的介入材料和技术，局部介入治疗已从传统的姑息性方法演变为肝转移瘤综合治疗体系中的重要组成部分。
