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钬激光前列腺剜除术后溶血性尿毒症综合征:一例报告

Hemolytic Uremic Syndrome Following Holmium Laser Enucleation of the Prostate: A Case Report.

作者信息

Krajewski Wojciech, Nowak Lukasz, Patrzałek Patryk, Tomczak Wojciech, Chorbinska Joanna, Laszkiewicz Jan, Malkiewicz Bartosz, Szydelko Tomasz

机构信息

University Center of Excellence in Urology, Department of Minimally Invasive and Robotic Urology, Wroclaw Medical University, Wroclaw, POL.

University Center of Excellence in Urology, Wroclaw Medical University, Wroclaw, POL.

出版信息

Cureus. 2025 Jun 9;17(6):e85599. doi: 10.7759/cureus.85599. eCollection 2025 Jun.

DOI:10.7759/cureus.85599
PMID:40636617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12240649/
Abstract

Holmium laser enucleation of the prostate (HoLEP) is a widely used surgical treatment for benign prostatic hyperplasia (BPH), and it is associated with a low incidence of severe complications. We report a rare case of hemolytic uremic syndrome (HUS) following HoLEP in a 71-year-old male. Shortly after the surgery, the patient developed altered consciousness, jaundice, and multiorgan failure, necessitating intensive care and renal replacement therapy. HUS was identified as the underlying cause. After a month-long hospitalization, the patient showed progressive renal recovery. This report underscores the importance of early recognition, multidisciplinary management, and close follow-up in achieving favorable outcomes in rare post-HoLEP complications.

摘要

钬激光前列腺剜除术(HoLEP)是治疗良性前列腺增生(BPH)广泛应用的手术方法,且严重并发症发生率较低。我们报告一例71岁男性患者在接受HoLEP术后发生溶血性尿毒症综合征(HUS)的罕见病例。术后不久,患者出现意识改变、黄疸和多器官功能衰竭,需要重症监护和肾脏替代治疗。HUS被确定为根本病因。经过为期一个月的住院治疗,患者肾脏功能逐渐恢复。本报告强调了早期识别、多学科管理以及密切随访对于罕见的HoLEP术后并发症取得良好预后的重要性。

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本文引用的文献

1
Comparison of holmium laser enucleation and transurethral resection of prostate in benign prostatic hyperplasia: a systematic review and meta-analysis.钬激光前列腺剜除术与经尿道前列腺电切术治疗良性前列腺增生的比较:系统评价和荟萃分析。
J Int Med Res. 2023 Aug;51(8):3000605231190763. doi: 10.1177/03000605231190763.
2
Atypical Hemolytic-Uremic Syndrome: Genetic Basis, Clinical Manifestations, and a Multidisciplinary Approach to Management.非典型溶血尿毒综合征:遗传基础、临床表现及多学科管理方法
J Multidiscip Healthc. 2023 Aug 4;16:2233-2249. doi: 10.2147/JMDH.S245620. eCollection 2023.
3
Utilization Pattern for Eculizumab Among Children With Hemolytic Uremic Syndrome.
依库珠单抗在溶血尿毒综合征患儿中的使用模式。
Front Pediatr. 2021 Oct 5;9:733042. doi: 10.3389/fped.2021.733042. eCollection 2021.
4
Rates and predictors of postoperative complications after Holmium laser enucleation of the prostate (HoLEP) at a high-volume center.大容量中心前列腺钬激光剜除术(HoLEP)术后并发症的发生率及预测因素。
Minerva Urol Nephrol. 2022 Aug;74(4):461-466. doi: 10.23736/S2724-6051.21.04315-9. Epub 2021 Apr 22.
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Shiga Toxin-Associated Hemolytic Uremic Syndrome: A Narrative Review.志贺毒素相关性溶血尿毒综合征:一篇叙述性综述。
Toxins (Basel). 2020 Jan 21;12(2):67. doi: 10.3390/toxins12020067.
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Global incidence of human Shiga toxin-producing Escherichia coli infections and deaths: a systematic review and knowledge synthesis.全球产志贺毒素大肠杆菌感染及死亡的发病率:一项系统综述与知识综合分析
Foodborne Pathog Dis. 2014 Jun;11(6):447-55. doi: 10.1089/fpd.2013.1704. Epub 2014 Apr 21.
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Holmium laser enucleation of the prostate and holmium laser ablation of the prostate: indications and outcome.钬激光前列腺剜除术和钬激光前列腺消融术:适应证与疗效
Curr Opin Urol. 2009 Jan;19(1):38-43. doi: 10.1097/MOU.0b013e32831a7008.
8
Shiga toxin-producing Escherichia coli infection.产志贺毒素大肠杆菌感染
Clin Infect Dis. 2004 May 1;38(9):1298-303. doi: 10.1086/383473. Epub 2004 Apr 15.