Zhang Qiong, Xiong Zhifeng, Gao Yuan, Zeng Min, Yang Huachao, Lyu Gang
Department of Breast, The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, China.
Department of Breast, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.
Front Oncol. 2025 Jun 25;15:1606116. doi: 10.3389/fonc.2025.1606116. eCollection 2025.
It is uncommon for breast cancer to present with distant metastasis as the initial symptom. This study reported a 67-year-old female patient with breast non-mass invasive ductal carcinoma, who sought medical attention due to abdominal distention, lower abdominal pain, constipation, hematochezia, and left-sided neck swelling. After a thorough examination, pathology confirmed the diagnosis of breast invasive ductal carcinoma, along with cervical lymph node and rectal metastasis. The non-specific breast symptoms in this case posed challenges for the early diagnosis of breast cancer. This also suggests that for breast cancer patients without a history of gastrointestinal disease, the presence of changes in bowel habits should raise suspicion for metastatic lesions. Imaging combined with biopsy pathology plays an important role in the diagnosis and treatment of non-mass breast cancer. This case also underscores the importance of breast health awareness and routine breast cancer screening among women, both for clinical practice and public health initiatives. Notably, early identification and diagnosis of non-mass breast cancer, coupled with the development of personalized treatment plans through multidisciplinary collaboration, are essential for enhancing treatment efficacy.
乳腺癌以远处转移作为首发症状并不常见。本研究报告了一名67岁女性患者，患有乳腺非肿块型浸润性导管癌，因腹胀、下腹痛、便秘、便血和左侧颈部肿胀前来就医。经过全面检查，病理确诊为乳腺浸润性导管癌，伴有颈部淋巴结和直肠转移。该病例中乳腺的非特异性症状给乳腺癌的早期诊断带来了挑战。这也表明，对于无胃肠道疾病史的乳腺癌患者，肠道习惯改变应引起对转移病灶的怀疑。影像学检查结合活检病理在非肿块型乳腺癌的诊断和治疗中起着重要作用。该病例还强调了女性乳腺健康意识和乳腺癌常规筛查的重要性，这对于临床实践和公共卫生举措都很重要。值得注意的是，非肿块型乳腺癌的早期识别和诊断，以及通过多学科协作制定个性化治疗方案，对于提高治疗效果至关重要。
