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10%强力霉素凝胶与1%葡萄糖酸氯己定凝胶对被……污染的喷砂酸蚀钛种植体表面消毒效果的比较评价

Comparative evaluation of the efficacy of 10% doxycycline gel and 1% chlorhexidine digluconate gel in the disinfection of sandblasted acid-etched titanium implant surface contaminated with .

作者信息

Kakarmath Sonal Vasudev, Gaikwad Rajesh P

机构信息

Department of Periodontology, Government Dental College and Hospital, Mumbai, Maharashtra, India.

出版信息

J Indian Soc Periodontol. 2025 Jan-Feb;29(1):34-41. doi: 10.4103/jisp.jisp_389_23. Epub 2025 Jun 10.

DOI:10.4103/jisp.jisp_389_23
PMID:40636768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12237173/
Abstract

AIM

The study evaluates the efficacy of 10% doxycycline gel and 1% chlorhexidine (CHX) gel in the disinfection of sandblasted acid-etched titanium implant surfaces contaminated with .

MATERIALS AND METHODS

Titanium implants were divided into two groups - Group A and Group B, which were further subdivided into three subgroups (A1, A2, and A3 and B1, B2, and B3). All the implants were contaminated with Group A was treated with 10% doxycycline gel, and Group B was treated with 1% CHX gel. After decontamination with antimicrobials, the residual viable count was assessed using the culture method.

RESULTS

At baseline, the mean values recorded for Group A and Group B were 120,000,000 colony-forming unit (CFU). On day 1, the mean values recorded were 3291.67 CFU (Group A1) and 0 CFU (Group B1). On days 3 and 7, the mean values for the remaining groups (A2, A3, B2, and B3) were 0 CFU.

CONCLUSION

A single application of 1% CHX gel and multiple applications of 10% doxycycline gel were effective in achieving decontamination of implants. Hence, these gels could prove as cost-effective treatment modalities for peri-implantitis.

摘要

目的

本研究评估10%强力霉素凝胶和1%氯己定（CHX）凝胶对被[具体污染物未给出]污染的喷砂酸蚀钛种植体表面的消毒效果。

材料与方法

将钛种植体分为A组和B组，每组再进一步细分为三个亚组（A1、A2、A3和B1、B2、B3）。所有种植体均被[具体污染物未给出]污染，A组用10%强力霉素凝胶处理，B组用1% CHX凝胶处理。用抗菌剂去污后，采用培养法评估残留活菌数。

结果

基线时，A组和B组记录的平均值为120,000,000菌落形成单位（CFU）。第1天，记录的平均值为3291.67 CFU（A1组）和0 CFU（B1组）。第3天和第7天，其余组（A2、A3、B2和B3）的平均值为0 CFU。

结论

单次应用1% CHX凝胶和多次应用10%强力霉素凝胶可有效实现种植体去污。因此，这些凝胶可被证明是治疗种植体周围炎的经济有效治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e915bb539bec/JISP-29-34-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/b590ae2d4c43/JISP-29-34-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/bf182308ce9a/JISP-29-34-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/3616585933c0/JISP-29-34-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/87c3b7474c66/JISP-29-34-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/448d6f789d9e/JISP-29-34-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/d5f05a027c34/JISP-29-34-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/1ce4d2f511c8/JISP-29-34-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/4d3a51363db5/JISP-29-34-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/2cd5eedea78f/JISP-29-34-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e5cdcba45000/JISP-29-34-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/c67999f1e59d/JISP-29-34-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e9d9b02eea62/JISP-29-34-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e915bb539bec/JISP-29-34-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/b590ae2d4c43/JISP-29-34-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/bf182308ce9a/JISP-29-34-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/3616585933c0/JISP-29-34-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/87c3b7474c66/JISP-29-34-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/448d6f789d9e/JISP-29-34-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/d5f05a027c34/JISP-29-34-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/1ce4d2f511c8/JISP-29-34-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/4d3a51363db5/JISP-29-34-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/2cd5eedea78f/JISP-29-34-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e5cdcba45000/JISP-29-34-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/c67999f1e59d/JISP-29-34-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e9d9b02eea62/JISP-29-34-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f97/12237173/e915bb539bec/JISP-29-34-g013.jpg

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