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肝脓肿作为穿孔性阑尾炎罕见的晚期并发症:病例报告

Hepatic Abscess as a Rare Late Complication of Perforated Appendicitis. A Case Presentation.

作者信息

Gerosa Martino, Roufael Francesca, Lasagna Chiara, Monte Fabiana Di, Sassun Richard, Sileo Annaclara, Santonocito Mauro, Vignati Barbara, Zarpellon Nicola, Cirocchi Roberto, Maggioni Dario, Mari Giulio Maria

出版信息

Chirurgia (Bucur). 2025 Jun;120(3):355-360. doi: 10.21614/chirurgia.3101.

DOI:10.21614/chirurgia.3101
PMID:40637072
Abstract

Acute appendicitis is a common surgical emergency, predominantly affecting young males. Although laparoscopic appendectomy reduces adverse outcomes, potential complications related to this condition are known. Among these, hepatic abscess is a rare and severe complication, with limited cases reported in the literature. Case Report: We report a case of an 18-years-old male with diffuse purulent peritonitis due to perforated appendicitis who developed a hepatic abscess one month post-surgery. Despite the initial management including surgical intervention and antibiotic therapy, after one month the patient presented with high temperature and right upper quadrant pain, leading to the discovery and subsequent percutaneous drainage of a hepatic abscess and intravenous antibiotic therapy. The abscess culture identified Bacteroides Fragilis, guiding targeted antibiotic therapy and resulting in a full recovery. This case highlights the potential for hepatic abscess formation following acute appendicitis, suspected to arise from hematogenous bacterial spread. Given the uncommon nature of this complication, a high index of suspicion in patients presenting with unusual symptoms post-appendectomy is required. Immediate percutaneous drainage alongside broad-spectrum antibiotic therapy, followed by targeted treatment upon pathogen identification, is crucial for managing this life-threatening condition. Conclusion: Although rare, hepatic abscess can occur as a complication of acute appendicitis, underscoring the importance of awareness and prompt intervention to prevent severe outcomes. Percutaneous drainage of the abscess associated to a targeted antibiotic therapy represents the treatment of choice.

摘要

急性阑尾炎是一种常见的外科急症,主要影响年轻男性。尽管腹腔镜阑尾切除术可减少不良后果,但已知与该病症相关的潜在并发症。其中,肝脓肿是一种罕见且严重的并发症,文献报道的病例有限。病例报告:我们报告一例18岁男性,因穿孔性阑尾炎导致弥漫性化脓性腹膜炎,术后一个月发生肝脓肿。尽管初始治疗包括手术干预和抗生素治疗,但一个月后患者出现高热和右上腹疼痛,导致肝脓肿被发现并随后进行经皮引流及静脉抗生素治疗。脓肿培养鉴定出脆弱拟杆菌,指导了针对性抗生素治疗并使患者完全康复。 该病例突出了急性阑尾炎后发生肝脓肿的可能性,怀疑是由血源性细菌传播引起。鉴于这种并发症的不常见性质,对于阑尾切除术后出现异常症状的患者需要高度怀疑。立即进行经皮引流并联合广谱抗生素治疗,随后根据病原体鉴定进行针对性治疗,对于处理这种危及生命的病症至关重要。结论:尽管罕见,但肝脓肿可作为急性阑尾炎的并发症发生,强调了提高认识和及时干预以预防严重后果的重要性。与针对性抗生素治疗相关的脓肿经皮引流是首选治疗方法。

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