有高钙尿症和无高钙尿症的尿路结石患者尿草酸排泄量的比较。

Comparison of urinary oxalate excretion in urolithiasis patients with and without hypercalciuria.

作者信息

Koide T, Bowyer R C, Brockis J G

出版信息

Br J Urol. 1985 Oct;57(5):505-9. doi: 10.1111/j.1464-410x.1985.tb05856.x.

DOI:10.1111/j.1464-410x.1985.tb05856.x

Abstract

The relationships between urinary oxalate, calcium and magnesium were investigated in 81 patients with idiopathic calcium oxalate urolithiasis on their regular diets. A significant relationship was established between calcium and oxalate excretion in the analysis of recurrent stone-formers (n = 44, P less than 0.01), though there was no significant difference between the two in the analysis of the patients overall or in single stone-formers. This suggests that recurrent stone-formers may have some abnormality of oxalate absorption in relation to calcium absorption. The role of calcium-oxalate interaction in the gut as a cause of mild hyperoxaluria is discussed.

摘要

对81例特发性草酸钙尿石症患者在常规饮食情况下尿草酸、钙和镁之间的关系进行了研究。在复发性结石形成者（n = 44，P < 0.01）的分析中，钙与草酸盐排泄之间建立了显著关系，尽管在总体患者分析或单发结石形成者分析中两者无显著差异。这表明复发性结石形成者可能在草酸吸收与钙吸收方面存在一些异常。讨论了肠道中草酸钙相互作用作为轻度高草酸尿症病因的作用。