Booth Amy, Breen Liz, Wieringa Sietse, Shaw Sara Elizabeth
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.
BMJ Lead. 2025 Jul 10. doi: 10.1136/leader-2025-001253.
Pharmaceutical manufacture, delivery and use produces an estimated 10%-55% of national healthcare greenhouse gas emissions. Addressing pharmaceutical supply chain emissions is essential to mitigating healthcare's climate impact. Our research aimed to explore the constraints to pharmaceutical supply chain climate action and how planetary health leadership can overcome these challenges.
We conducted 21 narrative interviews with representatives from pharmaceutical companies and industry and health system stakeholders. Interviews explored perspectives on climate action across pharmaceutical supply chains. Analysis was informed by argumentative discourse analysis, enabling the identification of key storylines.
Climate action across pharmaceutical supply chains is sporadic and insufficient to achieve health system climate goals. Critical constraints to climate action include (a) structural constraints, particularly complex, fragmented, global supply chains as well as limited renewable energy infrastructure in some countries where supply chains operate and (b) conceptual constraints, the 'patient-profit-planet dilemma', where climate action is perceived to conflict with patient well-being and financial considerations.Planetary health leadership can help overcome these constraints in three key ways. First, planetary health leadership can help reconceptualise healthcare delivery, and the role of pharmaceuticals, to align patient and planetary well-being while meeting financial pressures. Second, planetary health leadership can mobilise collective climate action across pharmaceutical supply chains, reframing climate change as a shared problem and challenging issues of transparency, competition and blame. Third, planetary health leadership can challenge wider systems that constrain climate action, leveraging the economic and political power of pharmaceutical supply chains to drive global decarbonisation efforts.
Planetary health leadership must confront considerable constraints to embed planetary health considerations across pharmaceutical supply chains. Leaders in this space must be willing to go against the status quo and challenge entrenched norms and systems to enable wider spread and support for sustainable healthcare delivery.
制药生产、供应和使用产生的温室气体排放量估计占国家医疗保健领域的10%-55%。解决制药供应链的排放问题对于减轻医疗保健行业对气候的影响至关重要。我们的研究旨在探索制药供应链气候行动的制约因素,以及全球健康领导力如何克服这些挑战。
我们对制药公司、行业以及卫生系统利益相关者的代表进行了21次叙事访谈。访谈探讨了制药供应链中气候行动的观点。分析采用了论证性话语分析方法,以确定关键的故事情节。
制药供应链中的气候行动是零星的,不足以实现卫生系统的气候目标。气候行动的关键制约因素包括:(a) 结构性制约因素,特别是复杂、分散的全球供应链,以及供应链运营所在的一些国家有限的可再生能源基础设施;(b) 概念性制约因素,即 “患者-利润-地球困境”,在这种困境中,气候行动被认为与患者福祉和财务考量相冲突。全球健康领导力可以通过三种关键方式帮助克服这些制约因素。首先,全球健康领导力可以帮助重新构想医疗保健服务以及药品的作用,在满足财务压力的同时,使患者福祉与地球福祉保持一致。其次,全球健康领导力可以推动制药供应链的集体气候行动,将气候变化重新界定为一个共同问题,并挑战透明度、竞争和责任归属等问题。第三,全球健康领导力可以挑战更广泛的制约气候行动的系统,利用制药供应链的经济和政治力量推动全球脱碳努力。
全球健康领导力在将全球健康考量纳入制药供应链的过程中必须面对相当大的制约因素。这一领域的领导者必须愿意打破现状,挑战根深蒂固的规范和系统,以实现对可持续医疗保健服务更广泛的推广和支持。