Li Songzhen, Shao Tianhang, Yao Shuyang
The First Clinical Medical College, Capital Medical University, Beijing 100053, China.
Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Zhongguo Fei Ai Za Zhi. 2025 Jun 20;28(6):467-471. doi: 10.3779/j.issn.1009-3419.2025.102.22.
Oligometastasis represents a transitional state between early localized disease and widespread metastasis, characterized by limited tumor burden and distinct tumor biological behavior. Due to the relatively restricted number of metastatic lesions and involved organs, aggressive systemic therapy combined with local consolidative therapy offers potential for cure. With rapid advancements in molecular targeted therapies and immunotherapy, comprehensive management of oligometastatic non-small cell lung cancer (NSCLC) has gained increasing attention. This review summarizes the definition of NSCLC oligometastasis, recent therapeutic progress, and existing challenges, aiming to provide insights for clinical diagnosis and treatment strategies. .
寡转移代表了早期局限性疾病和广泛转移之间的一种过渡状态,其特征是肿瘤负荷有限且具有独特的肿瘤生物学行为。由于转移病灶和受累器官的数量相对有限,积极的全身治疗联合局部巩固治疗提供了治愈的可能性。随着分子靶向治疗和免疫治疗的迅速发展,寡转移性非小细胞肺癌(NSCLC)的综合管理越来越受到关注。本综述总结了NSCLC寡转移的定义、近期治疗进展和现存挑战,旨在为临床诊断和治疗策略提供见解。