Ladipo O A, David-West A S
J Natl Med Assoc. 1977 Jul;69(7):485-7.
The results of Anti (D) immunoglobulin (RhoGAM) therapy in 25 Rh-negative women after delivery of Rh-positive babies are presented. None of the patients studied showed evidence of Rh-isoimmunization while two of 51 unprotected patients subsequently had antibodies detected in their serum. The incidence of Rh-negative patients is low in this environment. Because of the potential risk of isoimmunization, RhoGAM prophylaxis is advocated.
本文介绍了25名Rh阴性女性在分娩Rh阳性婴儿后接受抗D免疫球蛋白(RhoGAM)治疗的结果。在接受研究的患者中,没有一人出现Rh同种免疫的迹象,而51名未接受保护的患者中有两人随后血清中检测到抗体。在这种环境下,Rh阴性患者的发生率较低。由于存在同种免疫的潜在风险,提倡使用RhoGAM进行预防。