[Prevention of Rh sensitization using anti-D immunoglobulin. (An 8 year study)].

From July 1969 to July 1977 the authors administered 629 doses of anti D immunoglobulin to 597 women, 26 of them having received the preparation twice and 3 three times. The preparation of anti D immunoglobulin is most frequently given after delivery to Rh negative, in the ABO system compatible primiparae having given birth to a Rh positive child and being not immunized. The effectiveness of the prophylaxis was tested by sensibilization tests 3--6 months after delivery in 159 women, and in 1977, 137 more women were summoned to a follow-up, so that in all 296 women were hematologically followed up. The prophylaxis proved a failure in 0.6% of women. Biological control was carried out in a group of 118 women who had given birth to Rh positive children following the use of anti D immunoglobulin. It showed failure of the prophylaxis applied in 1.6% of cases.