Spoljarić I, Majnarić M
Jugosl Ginekol Opstet. 1978;18(5-6):417-22.
From July 1969 to July 1977 the authors administered 629 doses of anti D immunoglobulin to 597 women, 26 of them having received the preparation twice and 3 three times. The preparation of anti D immunoglobulin is most frequently given after delivery to Rh negative, in the ABO system compatible primiparae having given birth to a Rh positive child and being not immunized. The effectiveness of the prophylaxis was tested by sensibilization tests 3--6 months after delivery in 159 women, and in 1977, 137 more women were summoned to a follow-up, so that in all 296 women were hematologically followed up. The prophylaxis proved a failure in 0.6% of women. Biological control was carried out in a group of 118 women who had given birth to Rh positive children following the use of anti D immunoglobulin. It showed failure of the prophylaxis applied in 1.6% of cases.
1969年7月至1977年7月期间，作者共向597名妇女注射了629剂抗D免疫球蛋白，其中26人接受了两次注射，3人接受了三次注射。抗D免疫球蛋白制剂最常用于产后给ABO血型系统相容、分娩出Rh阳性婴儿且未产生免疫的Rh阴性初产妇。在159名妇女产后3至6个月通过致敏试验检测预防效果，1977年又有137名妇女被召回进行随访，因此共有296名妇女接受了血液学随访。结果显示，预防措施在0.6%的妇女中失败。对118名在使用抗D免疫球蛋白后分娩出Rh阳性婴儿的妇女进行了生物学对照。结果表明，所应用的预防措施在1.6%的病例中失败。
