Yang Yi, Wang Hong, Chen Zai Zhao, Teng Qi Rui
Jiang Xi University of Traditional Chinese Medicine, Nanchang, China.
Front Oncol. 2025 Jun 26;15:1617818. doi: 10.3389/fonc.2025.1617818. eCollection 2025.
Acupuncture is highly controversial in enhancing the quality of sleep and the risk of emotional maladjustment in breast cancer patients. Through a comprehensive meta-analytic approach, this study intends to investigate the effects of acupuncture on enhancing sleep quality and the risk of emotional maladjustment in patients diagnosed with breast carcinoma.
Search tactics aligned with Cochrane Collaboration recommendations. Systematic electronic searches were conducted in April 2025 across several data storage, including PubMed, Embase, Web of Science, the Cochrane Library, and Scopus. The reference lists of review essay were manually searched to refine potentially eligible studies. A pair of researchers independently performed a comprehensive literature review, conducted data extraction, and assessed the risk of bias. Outcome analysis included the quality of sleep and the risk of emotional maladjustment. For continuous measures, the pooled weighted mean difference (MD) and 95% confidence interval will be estimated. The meta-analysis was conducted using the Review Manager 5.3 and Stata 16.0 statistical software platforms.
A total of 11 studies involving 1116 participants were included. Statistically significant differences were found between acupuncture and control group in Pittsburgh Sleep Quality Index (PSQI) (MD = -1.38, 95%CI = -2.45 to -0.31), Insomnia Severity Index (ISI) (MD = -1.11, 95%CI = -3.68 to 1.45), Brief Fatigue Scale (BFI) score (MD = -2.30, 95%CI = -5.62 to -1.03). Acupuncture has been shown to Boost sleep quality and reducing the risk of emotional maladjustment. Specifically, it is manifested in: Hospital Anxiety and Depression Scale (HADS-A) (MD = -1.24, 95%CI = -2.41 to -0.35) and Hospital Anxiety and Depression Scale (HADS-D) (MD = -1.18, 95%CI = -2.15 to -0.20).
In comparison to other standard treatment modalities, acupuncture exhibits a notable distinction in boosting the sleep quality and the risk of emotional maladjustment of breast cancer patients. However, Clinicians should exercise caution when applying these results, as the available evidence suffers from methodological biases and quality limitations.
针刺疗法在改善乳腺癌患者睡眠质量及情绪失调风险方面存在高度争议。本研究旨在通过全面的荟萃分析方法，探究针刺疗法对确诊为乳腺癌患者睡眠质量及情绪失调风险的影响。
检索策略符合Cochrane协作网的建议。于2025年4月在多个数据存储库中进行系统的电子检索，包括PubMed、Embase、Web of Science、Cochrane图书馆和Scopus。人工检索综述文章的参考文献列表，以完善潜在符合条件的研究。由两名研究人员独立进行全面的文献综述、数据提取并评估偏倚风险。结果分析包括睡眠质量和情绪失调风险。对于连续性测量指标，将估计合并加权均数差（MD）及95%置信区间。使用Review Manager 5.3和Stata 16.0统计软件平台进行荟萃分析。
共纳入11项研究，涉及1116名参与者。针刺组与对照组在匹兹堡睡眠质量指数（PSQI）（MD = -1.38，95%CI = -2.45至-0.31）、失眠严重程度指数（ISI）（MD = -1.11，95%CI = -3.68至1.45）、简明疲劳量表（BFI）评分（MD = -2.30，95%CI = -5.62至-1.03）方面存在统计学显著差异。针刺疗法已被证明可提高睡眠质量并降低情绪失调风险。具体表现为：医院焦虑抑郁量表（HADS - A）（MD = -1.24，95%CI = -2.41至-0.35）和医院焦虑抑郁量表（HADS - D）（MD = -1.18，95%CI = -2.15至-0.20）。
与其他标准治疗方式相比，针刺疗法在提高乳腺癌患者睡眠质量及降低情绪失调风险方面表现出显著差异。然而，临床医生在应用这些结果时应谨慎，因为现有证据存在方法学偏倚和质量限制。
