Bowler Taylor, Tiegs Lyubov, Megna Bryant, Azeem Nabeel
Department of Internal Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA.
Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota Medical Center, Minneapolis, MN, USA.
J Med Cases. 2025 Jun 16;16(6):222-225. doi: 10.14740/jmc5127. eCollection 2025 Jun.
The development of non-cirrhotic portal hypertension and esophagogastric varices is an uncommon, yet life-threatening complication of splenic vein thrombosis. Recognizing this association between splenic vein thrombosis and non-cirrhotic portal hypertension is critical in reducing morbidity and mortality in patients with hypercoagulable disease secondary to malignancy. Herein, we present a 45-year-old female with stage IV high-grade serous ovarian carcinoma and chronic splenic vein thrombosis found to have life-threatening esophagogastric varices secondary to non-cirrhotic portal hypertension.
非肝硬化性门静脉高压症和食管胃静脉曲张的发展是脾静脉血栓形成的一种罕见但危及生命的并发症。认识到脾静脉血栓形成与非肝硬化性门静脉高压症之间的这种关联对于降低继发于恶性肿瘤的高凝疾病患者的发病率和死亡率至关重要。在此,我们报告一名45岁患有IV期高级别浆液性卵巢癌和慢性脾静脉血栓形成的女性,发现其患有继发于非肝硬化性门静脉高压症的危及生命的食管胃静脉曲张。