Ferguson A B
Clin Orthop Relat Res. 1985 Nov(200):291-8.
The segmental nature of the avascular involvement of the femoral head in both children and adults is similar. Avascular necrosis may be wrongly interpreted from roentgenograms in infancy, irregular ossification may be due to altered stress on the femoral head. The segment involved in Legg-Perthes' disease is superior and lateral to the fovea in an area supplied by a branch of the lateral epiphyseal artery. Secondary changes occur due to the separation of the dead segment from the living bone. Theron demonstrated the vascular interruption with micro-injection techniques in both child and adult. Finite analysis of the femoral head revealed the distortion of the computer model at the site of the branches of the lateral epiphyseal artery. Trauma with vascular interruption within the femoral head appears to explain the avascular segment.
儿童和成人股骨头缺血性坏死的节段性特征相似。婴儿期的X线片可能会对缺血性坏死做出错误解读，不规则的骨化可能是由于股骨头应力改变所致。Legg-Perthes病所累及的节段位于骨骺外侧动脉分支供血区域内，在中央凹的上方和外侧。由于坏死节段与存活骨质分离，继而发生继发性改变。Theron通过显微注射技术证实了儿童和成人的血管中断情况。对股骨头的有限元分析显示，计算机模型在骨骺外侧动脉分支部位发生了变形。股骨头内血管中断的创伤似乎可以解释缺血节段的形成。
