Shanker Uma, Rani Manviri, Kaur Navpreet
Department of Chemistry, Dr B R Ambedkar National Institute of Technology Jalandhar, Punjab 144008, India.
Department of Chemistry, Dr B R Ambedkar National Institute of Technology Jalandhar, Punjab 144008, India.
Food Chem. 2025 Nov 15;492(Pt 2):145466. doi: 10.1016/j.foodchem.2025.145466. Epub 2025 Jul 7.
Melamine, a nitrogen-rich industrial compound, is often illegally added to food products-especially dairy, to artificially inflate protein content, posing serious health risks such as kidney damage upon long-term exposure. This study aims to develop a fluorescence-based sensor for the sensitive detection of melamine. Nitrogen-doped carbon quantum dots (N-CQDs) were synthesized using Murraya koenigii leaves via a green, microwave-assisted method. Resulting N-CQDs exhibited a high fluorescence-quantum-yield of 30 %, and their structural and optical characteristics were thoroughly analysed using appropriate techniques. Detection mechanism is based on dynamic fluorescence quenching, allowing for highly responsive melamine-sensing with a low detection limit of 0.385 μM. When applied to real samples like water and milk, sensor demonstrated excellent performance, achieving recovery rates between 96.8 % and 101.8 % with low relative standard deviations (0.70 %-4.34 %). Results suggest that developed sensor is a promising tool for rapid, green, and sensitive detection of melamine in food safety and environmental monitoring.
三聚氰胺是一种富含氮的工业化合物，常被非法添加到食品中，尤其是乳制品中，以人为提高蛋白质含量，长期接触会带来严重健康风险，如肾脏损伤。本研究旨在开发一种基于荧光的传感器，用于灵敏检测三聚氰胺。利用微波辅助的绿色方法，以九里香叶为原料合成了氮掺杂碳量子点（N-CQDs）。所得N-CQDs表现出30%的高荧光量子产率，并使用适当技术对其结构和光学特性进行了全面分析。检测机制基于动态荧光猝灭，能够以0.385μM的低检测限对三聚氰胺进行高响应传感。当应用于水和牛奶等实际样品时，该传感器表现出优异的性能，回收率在96.8%至101.8%之间，相对标准偏差较低（0.70% - 4.34%）。结果表明，所开发的传感器是食品安全和环境监测中快速、绿色且灵敏检测三聚氰胺的有前途的工具。
