Bond W H
Clin Radiol. 1985 Nov;36(6):619-23. doi: 10.1016/s0009-9260(85)80247-6.
A retrospective study of 1703 Stage 1A and 1B adenocarcinomas of the uterine body, treated with and without post-hysterectomy vaginal irradiation in Birmingham between 1960 and 1974 inclusive, showed a vaginal failure rate of 3.76%. Vaginal irradiation eliminated recurrence in non-invasive tumours, and reduced the incidence in the invasive ones. Treatment had no influence on the incidence of pelvic recurrence, metastatic disease or the survival rate of any histological type of tumour, invasive or non-invasive. Treatment of late recurrence reduced the final vaginal failure rate to 0.83%. Prognosis depended on the size of uterine cavity, the histological grade and invasive character of the tumour, and was unrelated to post-operative local treatment.
一项回顾性研究对1960年至1974年(含)期间在伯明翰接受或未接受子宫切除术后阴道照射治疗的1703例子宫体1A期和1B期腺癌患者进行了分析,结果显示阴道复发率为3.76%。阴道照射消除了非浸润性肿瘤的复发,并降低了浸润性肿瘤的复发率。治疗对盆腔复发、转移性疾病的发生率或任何组织学类型肿瘤(浸润性或非浸润性)的生存率均无影响。对晚期复发的治疗将最终阴道复发率降至0.83%。预后取决于子宫腔大小、肿瘤的组织学分级和浸润特征,与术后局部治疗无关。