Ars Joan, Beridze Giorgi, Farrés-Godayol Pau, Pérez Laura M, Inzitari Marco, Calderón-Larrañaga Amaia, Welmer Anna-Karin
Aging Research Center, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet and Stockholm University, Widerströmska Huset, Tomtebodavägen 18 A, 171 65, Solna, Stockholm, Sweden.
RE-FiT Barcelona Research group. Vall d'Hebron Institute of Research (VHIR) and Parc Sanitari Pere Virgili, Barcelona, Spain.
Geroscience. 2025 Jul 12. doi: 10.1007/s11357-025-01756-w.
Regular physical activity (PA) and reduced sedentary behavior (SB) are well-established factors in promoting health and lowering the risk of chronic diseases. However, their relationship with unplanned hospitalizations remains unclear. Our aim was to investigate the associations between PA and SB parameters and the risk of unplanned hospital admissions, and the length of hospital stays in older adults. We analyzed data from 657 older adults aged ≥ 66 years from the Swedish SNAC-K study (2016-2018). The ActivPAL3 accelerometer was used to assess PA and SB. Multi-adjusted Cox and Laplace regressions were applied to examine PA and SB in relation to 6-year unplanned hospitalizations. Negative Binomial Regression models were employed to examine their associations with the length of hospital stays. For each 1000 steps/day, 100 low-intensity PA (LPA) walking events, and 15 min/day of time spent in moderate-to-vigorous PA (MVPA), the risk of unplanned admissions decreased (hazard ratio [HR] 0.95, 95% confidence interval [CI] 0.91-0.99, HR 0.77, 95%CI 0.61-0.96, and HR 0.91, 95%CI 0.83-1.00, respectively). Higher step counts and MVPA were also associated with shorter hospital stays (IRR per 1,000 steps: 0.91, 95% CI: 0.86-0.96; IRR per 15 min MVPA: 0.85, 95% CI: 0.75-0.96). No significant associations were found for SB or walking events with hospital stay in fully adjusted models. Our results suggest that higher step counts and greater participation in MVPA are associated with a reduced risk of hospital admissions and shorter hospital stays in older adults. Additionally, a greater number of LPA walking events was linked to lower risk of hospital admissions. These results support the promotion of regular walking and frequent PA as strategies to reduce healthcare burden in aging populations.
规律的体育活动(PA)和减少久坐行为(SB)是促进健康和降低慢性病风险的公认因素。然而,它们与非计划性住院之间的关系仍不明确。我们的目的是调查PA和SB参数与非计划性住院风险以及老年人住院时间之间的关联。我们分析了来自瑞典SNAC-K研究(2016 - 2018年)的657名年龄≥66岁的老年人的数据。使用ActivPAL3加速度计评估PA和SB。应用多因素调整的Cox回归和拉普拉斯回归来研究PA和SB与6年非计划性住院的关系。采用负二项回归模型来研究它们与住院时间的关联。每增加每天1000步、100次低强度PA(LPA)步行活动以及每天增加15分钟中等至剧烈强度PA(MVPA)时间,非计划性住院风险都会降低(风险比[HR]分别为0.95,95%置信区间[CI] 0.91 - 0.99;HR 0.77,95%CI 0.61 - 0.96;HR 0.91,95%CI 0.83 - 1.00)。更高的步数和MVPA也与更短的住院时间相关(每增加1000步的发病率比[IRR]:0.91,95% CI:0.86 - 0.96;每增加15分钟MVPA的IRR:0.85,95% CI:0.75 - 0.96)。在完全调整模型中,未发现SB或步行活动与住院时间有显著关联。我们的结果表明,更高的步数和更多地参与MVPA与老年人住院风险降低和住院时间缩短相关。此外,更多的LPA步行活动与更低的住院风险相关。这些结果支持将规律步行和频繁的体育活动作为减轻老年人群医疗负担的策略加以推广。
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