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大型和多发性子宫肌瘤机器人子宫肌瘤切除术的可行性及手术效果——来自单一中心十年经验的见解

Feasibility and surgical outcomes of robotic myomectomy for large and multiple uterine fibroids- insights from a decade of experience at a single centre.

作者信息

Sinha Rooma, Bana Rupa, Peddappolla Shilpa Chowdary

机构信息

Department of Gynaecology and Robotic Surgery, Apollo Health City, Hyderabad, India.

出版信息

J Robot Surg. 2025 Jul 11;19(1):377. doi: 10.1007/s11701-025-02538-4.

DOI:10.1007/s11701-025-02538-4
PMID:40646378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12254167/
Abstract

There is limited data on the safety and effectiveness of robotic-assisted myomectomy (RM) for large (≥ 8 cm) and multiple (≥ 5) fibroids. This study aims to assess the feasibility and perioperative outcomes of RM in these cases. A retrospective chart review was performed on 260 patients who underwent RM at a single institution between January 2013 and May 2024. Demographic information, primary symptoms, and operative outcomes were extracted from the patients' medical records. Large myomas were defined as those with a diameter of ≥ 8 cm, while multiple myomas were considered to be ≥ 5 fibroids. Data from 260 patients, with a mean age of 34.18 ± 5.55 years, were collected and analyzed. On average, 2.37 ± 0.31 fibroids were removed, with a mean weight of 294.0 ± 290.25 g. The average operative time was 144.6 ± 55.3 min, including a console time of 100.3 ± 47.13 min. The estimated blood loss (EBL) averaged 189.05 ± 296.65 mL, with 6.9% (18 patients) requiring transfusions. The mean hospital stay was 23.46 ± 6.42 h, with 87 patients staying more than 24 h. No conversions to laparotomy, reoperations, or major complications were reported. Patients with fibroids ≥ 8 cm experienced significantly higher EBL (p = 0.019), transfusion rates (p = 0.041), and longer hospital stays (p = 0.009). Although total operative time was not significantly affected by the number of fibroids, docking (p = 0.036) and console times (p < 0.001) were longer in patients with ≥ 5 fibroids. Additionally, blood transfusions were more frequently required in this group. Drawing on ten years of experience, this study highlights the feasibility and efficacy of RM in treating uterine myomas larger than 8 cm and in cases involving five or more fibroids.

摘要

关于机器人辅助子宫肌瘤切除术(RM)治疗大尺寸(≥8厘米)和多发性(≥5个)子宫肌瘤的安全性和有效性的数据有限。本研究旨在评估RM在这些病例中的可行性和围手术期结果。对2013年1月至2024年5月期间在单一机构接受RM的260例患者进行了回顾性病历审查。从患者的病历中提取人口统计学信息、主要症状和手术结果。大肌瘤定义为直径≥8厘米的肌瘤,而多发性肌瘤被认为是≥5个肌瘤。收集并分析了260例患者的数据,平均年龄为34.18±5.55岁。平均切除2.37±0.31个肌瘤,平均重量为294.0±290.25克。平均手术时间为144.6±55.3分钟,其中控制台操作时间为100.3±47.13分钟。估计失血量(EBL)平均为189.05±296.65毫升,6.9%(18例患者)需要输血。平均住院时间为23.46±6.42小时,87例患者住院时间超过24小时。未报告转为剖腹手术、再次手术或重大并发症的情况。肌瘤≥8厘米的患者EBL显著更高(p = 0.019)、输血率更高(p = 0.041)且住院时间更长(p = 0.009)。虽然肌瘤数量对总手术时间没有显著影响,但肌瘤≥5个的患者对接时间(p = 0.036)和控制台操作时间更长(p < 0.001)。此外,该组患者更频繁地需要输血。基于十年的经验,本研究强调了RM治疗大于8厘米的子宫肌瘤以及涉及五个或更多肌瘤病例的可行性和有效性。

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本文引用的文献

1
Feasibility and Perioperative Outcomes of Minimally Invasive Higher Order Myomectomy.微创高级子宫肌瘤剔除术的可行性和围手术期结果。
J Minim Invasive Gynecol. 2024 Oct;31(10):870-874. doi: 10.1016/j.jmig.2024.04.024. Epub 2024 May 3.
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Determination of Whole Blood Loss From Minimally Invasive Myomectomy Using a Standardized Formula: A Pilot Study.采用标准化公式测定微创子宫肌瘤剔除术的全血丢失量:一项初步研究。
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Multi-Port Robotic-Assisted Laparoscopic Myomectomy: A Systematic Review and Meta-Analysis of Comparative Clinical and Fertility Outcomes.多端口机器人辅助腹腔镜子宫肌瘤切除术:比较临床和生育结局的系统评价与荟萃分析
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Robotic Myomectomy: Five Modifications in Our Practice.机器人子宫肌瘤切除术:我们实践中的五项改进
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Robot-Assisted Laparoscopic Myomectomy versus Abdominal Myomectomy for Large Myomas Sized over 10 cm or Weighing 250 g.机器人辅助腹腔镜子宫肌瘤剔除术与开腹子宫肌瘤剔除术治疗大于 10 cm 或 250 g 的大肌瘤的比较。
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Comparison of operative time between robotic and laparoscopic myomectomy for removal of numerous myomas.机器人辅助子宫肌瘤剔除术与腹腔镜子宫肌瘤剔除术治疗多发性子宫肌瘤的手术时间比较。
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Epidemiology and management of uterine fibroids.子宫肌瘤的流行病学和管理。
Int J Gynaecol Obstet. 2020 Apr;149(1):3-9. doi: 10.1002/ijgo.13102. Epub 2020 Feb 17.
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Robotic myomectomy for large uterine myomas.大型子宫肌瘤的机器人子宫肌瘤切除术
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Robotic-assisted vs. laparoscopic and abdominal myomectomy for treatment of uterine fibroids: a meta-analysis.机器人辅助手术与腹腔镜及开腹子宫肌瘤切除术治疗子宫肌瘤的Meta分析
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