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大型和多发性子宫肌瘤机器人子宫肌瘤切除术的可行性及手术效果——来自单一中心十年经验的见解

Feasibility and surgical outcomes of robotic myomectomy for large and multiple uterine fibroids- insights from a decade of experience at a single centre.

作者信息

Sinha Rooma, Bana Rupa, Peddappolla Shilpa Chowdary

机构信息

Department of Gynaecology and Robotic Surgery, Apollo Health City, Hyderabad, India.

出版信息

J Robot Surg. 2025 Jul 11;19(1):377. doi: 10.1007/s11701-025-02538-4.

Abstract

There is limited data on the safety and effectiveness of robotic-assisted myomectomy (RM) for large (≥ 8 cm) and multiple (≥ 5) fibroids. This study aims to assess the feasibility and perioperative outcomes of RM in these cases. A retrospective chart review was performed on 260 patients who underwent RM at a single institution between January 2013 and May 2024. Demographic information, primary symptoms, and operative outcomes were extracted from the patients' medical records. Large myomas were defined as those with a diameter of ≥ 8 cm, while multiple myomas were considered to be ≥ 5 fibroids. Data from 260 patients, with a mean age of 34.18 ± 5.55 years, were collected and analyzed. On average, 2.37 ± 0.31 fibroids were removed, with a mean weight of 294.0 ± 290.25 g. The average operative time was 144.6 ± 55.3 min, including a console time of 100.3 ± 47.13 min. The estimated blood loss (EBL) averaged 189.05 ± 296.65 mL, with 6.9% (18 patients) requiring transfusions. The mean hospital stay was 23.46 ± 6.42 h, with 87 patients staying more than 24 h. No conversions to laparotomy, reoperations, or major complications were reported. Patients with fibroids ≥ 8 cm experienced significantly higher EBL (p = 0.019), transfusion rates (p = 0.041), and longer hospital stays (p = 0.009). Although total operative time was not significantly affected by the number of fibroids, docking (p = 0.036) and console times (p < 0.001) were longer in patients with ≥ 5 fibroids. Additionally, blood transfusions were more frequently required in this group. Drawing on ten years of experience, this study highlights the feasibility and efficacy of RM in treating uterine myomas larger than 8 cm and in cases involving five or more fibroids.

摘要

关于机器人辅助子宫肌瘤切除术(RM)治疗大尺寸(≥8厘米)和多发性(≥5个)子宫肌瘤的安全性和有效性的数据有限。本研究旨在评估RM在这些病例中的可行性和围手术期结果。对2013年1月至2024年5月期间在单一机构接受RM的260例患者进行了回顾性病历审查。从患者的病历中提取人口统计学信息、主要症状和手术结果。大肌瘤定义为直径≥8厘米的肌瘤,而多发性肌瘤被认为是≥5个肌瘤。收集并分析了260例患者的数据,平均年龄为34.18±5.55岁。平均切除2.37±0.31个肌瘤,平均重量为294.0±290.25克。平均手术时间为144.6±55.3分钟,其中控制台操作时间为100.3±47.13分钟。估计失血量(EBL)平均为189.05±296.65毫升,6.9%(18例患者)需要输血。平均住院时间为23.46±6.42小时,87例患者住院时间超过24小时。未报告转为剖腹手术、再次手术或重大并发症的情况。肌瘤≥8厘米的患者EBL显著更高(p = 0.019)、输血率更高(p = 0.041)且住院时间更长(p = 0.009)。虽然肌瘤数量对总手术时间没有显著影响,但肌瘤≥5个的患者对接时间(p = 0.036)和控制台操作时间更长(p < 0.001)。此外,该组患者更频繁地需要输血。基于十年的经验,本研究强调了RM治疗大于8厘米的子宫肌瘤以及涉及五个或更多肌瘤病例的可行性和有效性。

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本文引用的文献

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Robotic Myomectomy: Five Modifications in Our Practice.机器人子宫肌瘤切除术:我们实践中的五项改进
J Obstet Gynaecol India. 2022 Feb;72(1):89-92. doi: 10.1007/s13224-021-01553-3. Epub 2021 Oct 28.
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Epidemiology and management of uterine fibroids.子宫肌瘤的流行病学和管理。
Int J Gynaecol Obstet. 2020 Apr;149(1):3-9. doi: 10.1002/ijgo.13102. Epub 2020 Feb 17.
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Robotic myomectomy for large uterine myomas.大型子宫肌瘤的机器人子宫肌瘤切除术
Taiwan J Obstet Gynecol. 2018 Dec;57(6):796-800. doi: 10.1016/j.tjog.2018.10.004.

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