Ge Huan, Huang Zhenwu, Feng Jinghai, Zhang Minhong
State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Animals (Basel). 2025 Jun 30;15(13):1930. doi: 10.3390/ani15131930.
Summer high temperatures (27-38 °C, more than 7 days) readily induce heat stress in late-laying broiler breeders, which impedes offspring growth and development. This study aimed to provide a scientific basis for improving the offspring development of late-laying broiler breeders during summer. Six hundred fertilized eggs from 50-week-old LiFeng broiler breeders were divided into five treatment groups (non-injected, NaCl-injected, 6 mg/egg L-arginine-injected, 3.5 mg/egg L-methionine-injected, 8.4 mg/egg L-leucine-injected), with six replicates per group and 20 eggs per replicate. Embryos were incubated for 21 days and chicks raised for 21 days post-hatch. Methionine injection significantly enhanced hatchability (+5.8%), increased daily chick weight gain (+8.8%), reduced serum urea nitrogen (-53.13%), decreased inflammatory cytokine levels, elevated antioxidant enzyme activities, lowered malondialdehyde content (-47.99%), and suppressed expression of inflammatory and apoptotic pathway genes. The comprehensive effect of methionine was the best among the three amino acids when injected into chicken embryos. Methionine promoted protein synthesis, enhanced antioxidant and anti-inflammatory capacities, and consequently improved chick growth performance.
夏季高温（27-38°C，持续7天以上）很容易在产蛋后期的种鸡中引发热应激，这会阻碍后代的生长发育。本研究旨在为改善夏季产蛋后期种鸡的后代发育提供科学依据。将来自50周龄丽丰种鸡的600枚受精蛋分为五个处理组（未注射组、注射氯化钠组、每枚蛋注射6毫克L-精氨酸组、每枚蛋注射3.5毫克L-蛋氨酸组、每枚蛋注射8.4毫克L-亮氨酸组），每组六个重复，每个重复20枚蛋。胚胎孵化21天，雏鸡出壳后饲养21天。注射蛋氨酸显著提高了孵化率（提高5.8%），增加了雏鸡日增重（增加8.8%），降低了血清尿素氮水平（降低53.13%），降低了炎性细胞因子水平，提高了抗氧化酶活性，降低了丙二醛含量（降低47.99%），并抑制了炎性和凋亡途径基因的表达。当将蛋氨酸注射到鸡胚中时，其综合效果在三种氨基酸中最佳。蛋氨酸促进蛋白质合成，增强抗氧化和抗炎能力，从而改善雏鸡生长性能。
