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环境暴露增加儿童癌症幸存者的健康风险。

Environmental Exposures Increase Health Risks in Childhood Cancer Survivors.

作者信息

Shakeel Omar, Wood Nicole M, Thompson Hannah M, Scheurer Michael E, Miller Mark D

机构信息

Texas Children's Cancer and Hematology Center, Baylor College of Medicine, Houston, TX 77030, USA.

Children's Mercy Kansas City, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.

出版信息

Cancers (Basel). 2025 Jul 2;17(13):2223. doi: 10.3390/cancers17132223.


DOI:10.3390/cancers17132223
PMID:40647521
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12248912/
Abstract

Childhood cancer survivors (CCSs) are at increased risk for chronic health issues due to late effects of cancer and its treatment. We address the impact of environmental exposures, such as air pollution, tobacco smoke, extreme weather events, and pesticides, on the health and survival of CCSs. These environmental hazards have been associated with worsening health outcomes and decreased survival among CCSs on a global scale. We also highlight that providers at a major pediatric cancer center in the United States have limited knowledge and practical skills about environmental risk factors and how to reduce exposures. Our survey results show that pediatric oncology providers would find an environmental referral service helpful and useful in their department. Integrating environmental health into pediatric cancer care can empower patients and families, promote healthier behaviors, and potentially reduce morbidity and mortality in this vulnerable population.

摘要

儿童癌症幸存者(CCSs)由于癌症及其治疗的晚期效应,面临慢性健康问题的风险增加。我们探讨环境暴露因素,如空气污染、烟草烟雾、极端天气事件和农药,对CCSs健康和生存的影响。在全球范围内,这些环境危害与CCSs健康状况恶化和生存率降低有关。我们还强调,美国一家主要儿科癌症中心的医护人员对环境风险因素以及如何减少暴露的知识和实践技能有限。我们的调查结果显示,儿科肿瘤医护人员会发现环境转诊服务对他们所在科室有帮助且有用。将环境健康纳入儿科癌症护理可以增强患者及其家庭的能力,促进更健康的行为,并有可能降低这一弱势群体的发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaad/12248912/98239a726856/cancers-17-02223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaad/12248912/98239a726856/cancers-17-02223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaad/12248912/98239a726856/cancers-17-02223-g001.jpg

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本文引用的文献

[1]
Pre- and Postnatal Exposures to Residential Pesticides and Survival of Childhood Acute Lymphoblastic Leukemia.

Cancers (Basel). 2025-3-14

[2]
Climate change will impact childhood cancer risks, care and outcomes.

BMJ Paediatr Open. 2025-1-7

[3]
Ambient air pollution and survival in childhood cancer: A nationwide survival analysis.

Cancer. 2024-11-15

[4]
Residential proximity to oil and gas developments and childhood cancer survival.

Cancer. 2024-11-1

[5]
Morbidity and mortality among children, adolescents, and young adults with cancer over six decades: a Swedish population-based cohort study (the Rebuc study).

Lancet Reg Health Eur. 2024-5-15

[6]
Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade.

Int J Mol Sci. 2024-3-14

[7]
Health-related risk behaviors among U.S. childhood cancer survivors: a nationwide estimate.

BMC Cancer. 2024-2-6

[8]
Pre- and Postnatal Exposures to Tobacco Smoking and Survival of Childhood Acute Lymphoblastic and Myeloid Leukemias in California, United States.

Cancer Epidemiol Biomarkers Prev. 2024-1-9

[9]
Looking Towards 2030: Strengthening the Environmental Health in Childhood-Adolescent Cancer Survivor Programs.

Int J Environ Res Public Health. 2022-12-27

[10]
Social determinants of health and pediatric cancer survival: A systematic review.

Pediatr Blood Cancer. 2022-5

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