Stamatiou Konstantinos, Moschouris Hippocrates, Tzelepis Konstantinos, Perletti Gianpaolo, Magri Vittorio
Urology Department, Tzaneio General Prefecture Hospital, 18536 Piraeus, Greece.
Radiology Department, Tzaneio General Prefecture Hospital, 18536 Piraeus, Greece.
Diagnostics (Basel). 2025 Jun 23;15(13):1589. doi: 10.3390/diagnostics15131589.
: Currently, the Meares-Stamey 4-glass and the 2-glass tests are used for diagnosing chronic prostatitis subtypes. Both tests include prostatic massage. Failure to extract prostatic secretions-for any reason-can result in a non-diagnostic test. Evidence from everyday practice and studies shows that expressed prostatic secretions are successfully recovered in less than 50% of the examined patients, and an important number of post-massage urine samples are missing prostatic secretions. This study evaluated a simpler test, the 3-glass (pre-ejaculation, ejaculation, and post-ejaculation) test. We compared it with the 4-glass and the 2-glass tests to detect inflammation and bacteria in men with chronic prostatitis symptoms. The study population included patients with chronic prostatitis symptoms. Subjects were assigned in each visit to undergo either the 4-glass, the 2-glass test, or the 3-glass test. The comparison among the three tests was based on the percentage of bacterial detection, the percentage of false-negative diagnoses, and the percentage of shifts among chronic prostatitis subtypes in the follow-up visits of recurrent patients. A total of 157 patients were finally evaluated. Fifty-nine (59) patients underwent the 4-glass test (Group A), sixty-seven (67) underwent the 3-glass test (Group B), and thirty-one (31) underwent the 2-glass test (Group C). No statistically significant differences in the comparisons above were found. : A comparison of the three diagnostic tests showed equivalence of the total ejaculate culture-based 3-glass test to the conventional prostatic secretion culture-based tests.
目前，Meares-Stamey四杯法和两杯法检测用于诊断慢性前列腺炎的亚型。两种检测方法均包括前列腺按摩。由于任何原因未能获取前列腺分泌物都可能导致检测结果无法诊断。日常实践和研究证据表明，在不到50%的受检患者中能够成功获取前列腺分泌物，并且大量按摩后的尿液样本中缺少前列腺分泌物。本研究评估了一种更简单的检测方法，即三杯法（射精前、射精时和射精后）检测。我们将其与四杯法和两杯法检测进行比较，以检测有慢性前列腺炎症状男性的炎症和细菌。研究人群包括有慢性前列腺炎症状的患者。每次就诊时，受试者被分配接受四杯法、两杯法检测或三杯法检测。三种检测方法之间的比较基于细菌检测百分比、假阴性诊断百分比以及复发患者随访中慢性前列腺炎亚型之间的转换百分比。最终共评估了157例患者。59例患者接受了四杯法检测（A组），67例接受了三杯法检测（B组），31例接受了两杯法检测（C组）。在上述比较中未发现统计学上的显著差异。三种诊断检测方法的比较表明，基于总射精液培养的三杯法检测与基于传统前列腺分泌物培养的检测方法等效。
